Flashcards in Influenza Deck (10)
Loading flashcards...
1
Pathophysiology
Spread: droplet
Incubation: 1-4d
Infectivity: 1d before symptoms start to 7d after
Immunity: only strains which have already attacked pt
2
Presentation
Fever
Headache
Malaise
Myalgia
N/v
Conjunctivitis
3
Complications
Bronchitis
Pneumonia: esp. Staph
Sinusitis
Encephalitis
Pericarditis
Reyes: rash, vomiting, ↑LFTs in children give aspirin
4
Ix
Bloods: lymphopenia,
thrombocytopenia
Culture: 1wk from nasal swabs
PCR: takes 36h
5
Mx
Bed rest + paracetamol
If severe:
- ITU
- Cipro and co-amoxiclav: prevent Staph and Strep
- Oseltamivir
- Neuraminidase inhibitor
Zanamivir:
Inhaled NA inhibitor active
6
Prevention
Good hygiene
Trivalent Vaccine
7
Who is offered the flu vaccine
>65yrs
DM, COPD, heart, renal, liver failure
Immunosuppression: splenectomy, steroids
Medical staff
8
Haemagglutinin
Surface antigen which binds to cells of infected person
9
Neuraminidase
Surface antigen that releases the virus from the host cells
10
