Innate and adaptive immunity Flashcards Preview

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Flashcards in Innate and adaptive immunity Deck (18)
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1
Q

Defensins are natural antibiotics produced by epithelia. True or false?

A

True

2
Q

What is the advantage of increased vascular permeability promoted by inflammatory mediators?

A

It allows increased migration of macrophages, neutrophils and lymphocytes into tissue

3
Q

Which type of innate immune system cell is involves in the anti parasite and allergy response?

A

Eosinophil

4
Q

Basophil’s are involved in the protection of mucosal surfaces. True or false?

A

True

5
Q

Are macrophages a part of the innate or adaptive immune response?

A

Innate

6
Q

What is the role of T helper cells?

A

To activate B lymphocytes

7
Q

What is the role of cytotoxic T lymphocytes?

A

To kill virus infected cells

8
Q

Which lymphocyte: T or B? Has a cell antigen receptor is a membrane-bound antibody surface immunoglobin.

A

B lymphocyte

9
Q

What are the three main ways in which antibodies protect the host from infection?

A
  • Neutralization
  • Oponisation
  • Complement activation
10
Q

What is clonal selection?

A

It is the process where by the clonal frequency of cells with a particular antigen specificity is raised

11
Q

What are plasma cells?

A

Cells derived from B lymphocytes that produce antibodies

12
Q

What is complement activation?

A

It is where the antibody activates a complement, which enhances oponization and lyses some bacteria

13
Q

Pus is an accumulation of dead neutrophils. True or false?

A

True

14
Q

What is oponization?

A

It is the coating of a microorganism by antibodies or complement to render it recognisable as foreign by phagocytes, thus enhancing phagocytosis.

15
Q

How do natural killer cells directly induce apoptosis in virus-infected cells?

A

By pumping proteases through pores

16
Q

What is the complement system?

A

It marks pathogens for destruction by covalently biding to their surface. It enhances the oponising effects of bacteria

17
Q

Give me an example of a secretory molecule of the innate immune system. (7)

A
  • Transferrine and lactoferrin
  • Interferon
  • Lysosomes
  • Antimicrobial peptides
  • Fibronectin
  • Complement component
  • TNF-alpha
18
Q

What is the body’s first defence against infection?

A

Epithelia