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ANATOMY KAPLAN FOR THE USMLE > integument > Flashcards

Flashcards in integument Deck (19):
1

Integument consists of ?

Skin ( epidermis and dermis)
associated appendages ( Sweat glands, sebaceous glands, hairs, nails)

2

How many layers does the epidermis has ?

Stratum basal
Stratum spinosum
Stratum granulosum
stratum lucidum
stratum corneum

3

How many cell types does the epidermis contains ?

keratinocytes
Melanocytes
langerhan cells
Merkel cells

4

Melanocytes are derived from ?

Neural crest ectoderm

5

Pemphigus is an ?

Autoinmune disease with blistering by disruption of desmosomes linking keratinocytes.

6

Psoriasis is a disease where ......

AN increase of the proliferating cells in the basal area and spinosum area increase the rate of cell turnover, this results in greater epidermal thickness and turnover of the epidermis

7

The integument functions are ?

1) protect from injury, desiccation, and infection
2) Thermoregulation
3)water balance
4) sensory reception
5) excretion

8

Albinism is produced by ?

Melanocytes cant produce melanin

9

Vitiligo is produced by ?

Autoinmune disease with antibodies against melanocytes

10

Bullous pemphigoid is ?

An autoinmune disease with blistering disorders of the dermis-epidermis junction or hemidesmosomes.

11

The dermis formed of ?

Connective tissue of mesodermal origin

12

Why the dermis-epidermis junction is important ?

increases the surface area of attachment and brings blood vessels in closer proximity to the epidermal cells

13

The hypodermis is a layer of mainly ?

Loose vascular connective tissue and adipocytes, and attaches skin to underlying muscles.

14

which aspects differentiate an eccrine vs an apocrine gland ?

Eccrine: is all over skin release content into skin surface.
Apocrine: NAsty axilary areolar and anal region

15

Where does an apocrine and eccrine gland sites of opening are ?

Apocrine: hair follicles
Eccrine: Skin surface

16

Apocrine vs eccrine secretions ?

Apocrine: viscous and nasty under adrenergic control
Eccrine: watery low proteins mainly H2O under cholinergic control

17

Sebaceous glands are what kind of glands?

Branched holocrine acinar glands, the discharge their secretions within hair follicles.
Lubricate skin and cornified layers.

18

Which stratum has demsosomes ?

Stratum espinosum

19

The sum of :
A follicle + sebaceous gland is called ?

The pilosebaceous units.