Flashcards in Intra-abdominal infection and gastroenteritis Deck (28):
Blood tests for intra-abdo infection
LFTs abnormal in hepatobiliary disease
Imaging in intra-abdo infection
CXR- consolidation, effusion, low lobe pneumonia can present as abdo pain
USS- masses, free fluid, dilated bile ducts
Rx of abscess
Antibiotics for source other than intestinal?
Depends on source
Flora of GI tract that might cause intra-abdo infection
Are there more obligate anaerobic bacteria or facultative anaerobes in the colon?
List the pathongens that cause gastroenteritis
(and can also get non-infective)
Complications of gastroenteritis
Haemolytic uraemic syndrome
What tests would you do on a stool sample for gastroenteritis
OCP- ova, cysts, parasites
MC&S- microscopy, culture and sensitivity
C. diff toxin
How is cryptosporidium gastroenteritis spread?
waterborne (oocytes resistant to chlorine based disinfectants)
Which bacterial causes of gastroenteritis produce enterotoxins?
Which bacterial causes of gastroenteritis have a mechanism of adherence to cells?
What is the affect of the E. Coli strain EHEC/VTEC
What is the affect of the E. Coli strain ETEC
What is the affect of the E. Coli strain EAggEC
What is the affect of the E. Coli strain EIEC
Enteroinvasive dysentry like
What is the affect of the E. Coli strain EPEC
E. Coli strain 0157 uses what virulence factor?
Shiga toxin virulence factor
Source of E coli 0157?
Severe complication of 0157?
Haemolytic uraemic syndrome in 10-15% because acts on RBCs
Mechanism of 0157 toxin
Similar to cholera- g proteins activated, more cAMP, more ion channels activated, increased Cl efflux, water follows into the gut.
Why can killing the bacteria make e coli worse?
More toxins released
Does salmonella produce a toxin?
4 strains of salmonella
Typhoidal strains of salmonella......?
affect cells outside of the GI tract also
Treatment of gastroenteritis?
Avoid Abx except:
-Spread outside GI tract (+ve blood culture)
C. diff treatment