Intro to Pharm Flashcards
drug ending in -lol is most likely a
beta blocker
drug ending in -sin is most likely a
alpha blocker
drug ending in -pril is most likely a
ACE inhibitor
drug ending in -pine is most likely a
calcium channel blocker
drug ending in -ide is most likely a
diuretic agent
list some drugs with low TI (as mentioned in Iszard’s lecture)
digoxin lithium warfarin theophylline pheytoin gentamicin amopheticin B t-fluorouracil
describe additive chemical interactions
2+3=5
- just add the effects of both drugs together to get the final result
describe synergistic chemical interactions
3+3=9
- the drugs multiply each other to get a larger result
describe potentiated chemical interactions
2+0=4
- a drug that is normally non-effective on its own potentiates the effect of another drug
- EtOH + CCl4
describe functional antagonism
two agonists interact with different receptors to produce opposite effects
- adrenergic drug increases HR and BP and a vasodilator decreases BP (overall effect is an increased HR)
describe chemical antagonism
a drug counters the effect of another, resulting in decreased effect
- CaNa2 EDTA counteracts Pb and As poisoning
describe dispositional antagonism
metabolism of a chemical is altered and the concentration and/or duration of the chemical are diminished
- using ethanol to treat methanol poisoning (ethanol will compete for ethanol dehydrogenase and block methanol break down)
describe receptor antagonism
administering a drug that outcompetes a toxin for a specific receptor
- opioids
what are “A” coded drugs
drug products that are considered to be therapeutically equivalent to other pharmaceutically equivalent products
what are “B” coded drugs
drug products that are NOT considered to be therapeutically equivalent to other pharmaceutically equivalent products
what is mEq
milliequivalents (1/1,000th of an equivalent)
kg to lb
1 kg = 2.2 lbs
tsp to mL
1 tsp = 5 mL
tbsp to mL
1 tbsp = 15 mL
oz to mL
1 oz = 30 mL
mL/cc to L
1 mL/cc = 1/1,000 liter
quart to mL
1 quart = 946 mL
pint to mL
1 pint = 473 mL
gallon to L
1 gallon = 3.79 L
