Introduction to Nervous System Flashcards

(28 cards)

1
Q

Name of cell body of Neuron

A

Perikaryon

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2
Q

Compare the synaptic contacts of the perikaryon and dendrites vs the axon

A

The perikaryon and dendrites have hundreds to thousands of dendritic contacts while axons have few or none

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3
Q

Glial Cells

A

These cells are the helper cells of the nervous system and are necessary for a neuron to survive
They cover the parts of a neuron that is not covered by synapses

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4
Q

What covers the neuronal cell surface between synaptic contacts

A

Glial Cells (You never walk alone principle)

Thus there is no neuronal surface exposed to extracellular matrix fluid

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5
Q

Why are mitochondria found on pre-synaptic clefts

A

Providing ATP necessary for vesicle recycling and transmitter synthesis

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6
Q

Type of conduction caused by myelin sheaths

A

Saltatory Conduction

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7
Q

Describe the structure of Myelin Sheaths

A

Tightly spiralled, very thin layers of Schwann cells

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8
Q

Describe the shape of a Multipolar, Bipolar and Pseudo-Unipolar Neuron

A
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9
Q

What nerves are contained in the CNS and which in the PNS

A

Central Nervous System includes brain and spinal cord - nerve cell bodies and voluntary nervous system

Peripheral NS includes axons and dendrites travelling through the rest of the body

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10
Q

Discuss the casing of CNS nerves

A

CNS is encased by a minimally permeable, multi-layered tough connective tissue sheet

The meninges (membranes) lie inside a bone casing; fluid inside meninges is called CSF which has a different composition to interstitial fluid of the rest of the body

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11
Q

Grey Matter vs White Matter

A

White Matter: Areas with mostly dendrites/axons due to the high lipid proportion of myelin sheaths

Grey Matter: Areas with many cell bodies have more blood supply and mitochondria

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12
Q

What type of neurons are sensory neurons and why

A

Pseudo-unipolar Neurons

To allow dendrite and axon as uninterrupted strand for maximal speed of transduction

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13
Q

What type of neurons are sensory neurons and why

A

Pseudo-unipolar Neurons

To allow dendrite and axon as uninterrupted strand for maximal speed of transduction

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14
Q

Shape of Motor Neuron

A

Shape of Classic textbook neuron - Multipolar

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15
Q

Where is the perikaryon of a sensory neuron located

A

Spinal Ganglion - Just outside the border between CNS and PNS (In PNS) while some of its axons are in CNS

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16
Q

In reflex arcs, describe the distribution of motor neurons

A

Perikaryon of motor neuron is in CNS along with dendrites but most of the axon is in PNS

17
Q

How do nerves tend to run when in between muscles

A

Grooves (Septa) for protection

Separating spaces between muscles

18
Q

Annotate this cross section of a peripheral nerve

19
Q

Epineurium

A

Collagenous connective tissue (Dense)

Lining of Nerve

20
Q

Perineurium

A

Sheath with flat cells of epithelial character with collagen fibres between them; it bundles axons into fascicle and forms a seal
Lining of individual fascicles

21
Q

Endoneurium

A

Loose connective tissue between axons/dendrites in a fasicle; adapted for maintaining the fascicle

22
Q

Fascicle

A

Bundles of nerves/axons/dendrites

23
Q

How do non-myelinated axons adhere to the never walk alone principle

A

Being hugged by Schwann cells but not wrapped in dozens of layers that would otherwise create myelin

24
Q

How to differentiate between blood vessels and nerves in a stain

A

Larger blood vessels may have an RBC in them and a thick outline generally

Nerves tend to be wavy with elongated nuclei
Often reddish rings with whitish content when cross sections

25
Dorsal Root Ganglia
Site of sensory (pseudo-unipolar) nerve cell bodies
26
Where do nuclei seen in a dorsal root ganglion's cross section outside the perikaryon come from
Satellite cells
27
Role of Myelin Sheaths
Insulators
28
Do myelin sheaths create white or gray matter
White due to the high fatty acid content