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Flashcards in Iron deficiency Deck (13)
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1

Explain the role of iron in erythropoiesis

20mg required per day
= fuel for erythropoiesis

2

Recall 2 possible causes of iron loss

Desquamated cells of skin/ gut
Menstruation

3

Recall how much iron is provided by the human diet daily, and the main sources of this

12-15mg/day
Meat, fish, vegetables, whole grain cereals, chocolate

4

In what state is iron absorbed?

Ferrous Fe2+

5

What is the cellular iron exporter called and how is it controlled?

Ferroportin:
controlled by HEPICIDIN (which is controlled by negative feedback of iron)

6

What binds iron in circulation?

Transferrin

7

Recall 4 causes of iron deficiency

Bleeding
Increased usage (growth/ pregnancy)
Dietary deficiency
Malabsorption (coeliac)

8

What are the 2 possible main clinical features of iron deficiency

IDA or ACD

9

What is the main haematological feature of iron deficiency

Microcytic erythrocytes

10

Recall the serum iron level in IDA, ACD and thalassaemia

IDA: low
ACD: low
thalassaemia: high

11

Recall the ferritin level in IDA, ACD and thalassaemia

IDA: low
ACD: high
Thalassaemia: high

12

Recall the transferrin level in IDA and ACD

IDA: low
ACD: normal or low

13

What is the equivalent test to transferrin levels?

Total iron binding capacity