Irritable bowel Syndrome Flashcards Preview

Liver + GI > Irritable bowel Syndrome > Flashcards

Flashcards in Irritable bowel Syndrome Deck (12):
1

probable aetiology

due to disorders of intestinal motility or enhanced visceral perception

'brain-gut' axis

2

History of symptoms

chronic, >6 months,
exacerbated by stress, menstruation or gastroenteritis

3

signs

Examination often normal
general abd tenderness
Examination rectal/abd mass

4

Criteria

Pain is either relieved by defecation or associated with altered stool form or bowel frequency (constipation and diarrhea may alternate)

AND ≥2 of: urgency, incomplete evacuation, abd bloating/distension, mucous PR, worsening of symptoms after food.

5

Diagnostic tets

normal bloods

initial: coeliac serology (tTG, IgA Endomesial antibodies)

further: faecal calprotectin, colonoscopy, CA125, TSH

6

DDx

coeliac disease, lactose intolerance, bile acid malab, IBD, colorectal cancer

7

Tx constipation

avoid insoluble fibre

Laxatives e.g. bisacodyl

8

Tx diarrheoa

avoid sorbitol sweeteners
bulking agent + loperamide (an anti motility agent) after each lose stool

9

Tx pain

oral antispasmodics (a.k.a anticholinergics)

e.g. benzatropine

block ACh in the brain

10

Tx psychological symptoms

CBT, hypnosis

11

Name a tricyclic antidepressant and when you'd use it

+ its main SE

amitriptyline

when nothing else works

SE: drowsiness, 4-6 weeks to take effect

NOT for depression

12

epidemiology

10-20%
F>M