Is the drug class bactericidal or bacteriostatic (+MOA)? Flashcards Preview

IDMM > Is the drug class bactericidal or bacteriostatic (+MOA)? > Flashcards

Flashcards in Is the drug class bactericidal or bacteriostatic (+MOA)? Deck (18):
1

Glycopeptides

Bactericidal- cell wall synthesis inhibition

2

Lipopeptides

Bactericidal- disruption of cell wall membrane

3

Aminoglycosides

Bactericidal- binds to 30S subunit

4

Macrolides

Bacteriostatic- binds to 50S subunit

5

Lincosamides

Bacteriostatic- binds to 50S subunit

6

Tetracyclines

Bacteriostatic- binds to 30S (and 50S?)

7

Glycylcyclines

Bacteriostatic- binds to 30S (and 50S?)

8

Fluroquinolones

Bactericidal- inhibit DNA gyrase and topoisomerase

9

Anti-folates

Bacteriostatic (Nitrofurantoin bactericidal but only achieves therapeutic concentration in urine)- inhibit enzymes in folate pathway

10

Nitroimidazoles

Bactericidal- inhibit DNA synthesis

11

Oxazolidinones

Bacteriostatic- binds to 50S

12

Rifampin

Bactericidal- binds RNA pol

13

Isoniazid

Bactericidal- inhibits mycolic acid synthesis

14

Pyrazinamide

Bactericidal- inhibits mycolic acid synthesis

15

Ethambutol

Bactericidal- inhibits polymerization of arabinoglycan in mycobacterial wall

16

Penicillins

Bactericidal- cell wall synthesis inhibitor

17

Carbapenems

Bactericidal- cell wall synthesis inhibitor

18

Cephalosporins

Bactericidal- cell wall synthesis inhibitor