Ischemic Heart Disease Flashcards Preview

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Flashcards in Ischemic Heart Disease Deck (7)
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1
Q

Cardiac stress testing can be done pharmacologically. Pharmacologic stress testing can utilize all of the following medications except:

A. Dobutamine
B. Dipyridamole
C. Lexicon
D. Dopamine
E. Adenoscan
A

D. Dopamine

2
Q

What is the most common dose of nitroglycerin in short-acting products? (GoNitro, NitroMist, Nitrostat)?

A. 400 micrograms
B. 0.4 micrograms
C. 40 micrograms
D. 4 micrograms
E. 4 milligrams
A

A. 400 micrograms
Each spray of nitrolmist and each packet of GoNitro provides 400 micrograms
Nitrostat (SL tablets) comes in 0.3, 0.4 and 0.6 milligrams

3
Q

KJ has an increased risk of bleeding due to the combination of which two medications?

A. plavix and fosinopril
B. Plavix and prozac
C. Lopressor and prilosec
D. Atorvastatin and plavix
E. Lopressor and prozac
A

B. Plavix and prozac
Additive effects can be seen when used in combination with SSRIs

Prozac = fluoxetine
Lopressor = metoprolol
Prilosec = omeprazole
4
Q

Which of the following statements is correct regarding nitroglycerin ointment?

A. This medication can stain clothing
B. This medication should be applied from the tube directly to the skin
C. A brand name for this product is Nitro-Dur
D. This medication should be applied every 4 hours around the clock
E. This medication can be used safely with Cialis

A

A. It can stain clothing
a 10-12 hour nitrate-free period is required to prevent tachyphylaxis (tolerance)
Nitro-Dur is a patch
Ointment is Nitro-BID
measure dose using measuring applicator and spread it using the applicator provided

5
Q

Which of the following drug classes is preferred for the treatment of Prinzmetal’s (variant) angina?

A. Nitrates
B. Antiplatelets
C. Beta blockers
D. Calcium channel blockers
E. Ranolazine
A

D. CCBs

6
Q

Choose the correct statement concerning ranolazine:

A. Ranolazine decreases myocardial oxygen demand by decreasing heart rate and blood pressure
B. Ranolazine is only indicated as mono therapy for treating chronic angina, not as combination therapy
C. Ranolazine has no significant drug interactions to be concerned about
D. One of the warnings associated with the use of ranolazine is a risk of QT prolongation
E. Ranolazine is preferred for patients with Prinzmetal’s (variant) angina

A

D. Risk of QT prolongation

Ranolazine does not effect heart rate and BP
It is a major substrate of 3A4
Can be used as add-on therapy or in place of beta blockers when they are contraindicated

7
Q

HG uses Minitran 0.6 mg/hr applied daily for stable ischemic heart disease. which of the following is true?

A. This patient does not need a short-acting nitroglycerin product for acute chest pain episodes
B. This is a transdermal patch; the preferred site of application is the chest
C. The patient should remove used patches every morning (after 20-24 hours of use)
D. The site of application should be rotated every 2 weeks
E. This is the preferred form of nitroglycerin use in combination with hydrazine in patients who have heart failure

A

B. The preferred site of application is the chest

Should be applied in the morning and removed after 12-14 hours.
The site of application should be rotated
Long-acting nitrates are used in combination with other drugs and should not be first line for chronic stable angina