Flashcards in Kaplana 1 Deck (50):
Transient Erythroblastopenia of Childhood (TEC)
most common acquired pure red cell aplasia in kids
presents 6 mos to 3 years after viral illness; transient immune suppression of RBC production
Follow over 1-2 months for spontaneous resolution. transfusions may be indicated in unusual cases with hemodynamic compromise.
kid from mexico, ultrasound shows liver abscess. Next step?
serum antibody testing for entamoeba amebiasis
treat with metronidazole
apical click followed by late systolic murmur
mitral valve prolapse. Expect normal sized heart, normal ECG or with unifocal/ multifocal PVCs and biphasic T waves.
Echo shows posterior movement of posterior leaflet of valve.
microhematuria after minor trauma in kid
do an ultrasound of kidneys, ureter, and bladder in case of congenital anomaly or blunt trauma injury. If normal, redo urinalysis over next 2 weeks.
what indicates good prognosis in juvenile rheumatoid arthritis (oligoarticular)?
positive antinuclear antibodies.
first sign of premature puberty
most common inherited intellectual disability/ causeof autism
amplification of trinucleotide sequence of FMR1 on X chromosome
in full mutation- absent gene product
ulcerative colitis antibodies, commonly
hereditary hypophosphatemic rickets
vitamin D-resistant rickets
slow growth, rickets
urinary excretion of phosphate is high.
Jervell-Lange Nielsen syndrome
recurring episodes of torsades de pointes or ventricular fibrillation (ventricular arrhythmias)
sterp pharyngitis complications... what doesn't get prevented with antibiotics?
treat with penicillin; with allergy, macrolide.
Complications: rheumatic fever, glomerulonephritis, peritonsillar abscess, and retropharyngeal abscess
glomerulonephritis not preventable with abx (immune mediated reaction)
trisomy 21 heart defect?
endocardial cushions defect (both ASD and VSD that are contiguous)
cough, coryza and conjunctiitis --> rash that starts at the head and spreads to trunk and limbs
Koplik spots (red with blue/white centers) on mucous membranes of mouth
complication: acute otitis media
What to do for foreign body aspiration?
rigid bronchoscopy under anesthesia because greater access to the subglottic airways, optimal passage and extraction while maintaining adequate oxygenation of the patient
infantile hemangiomas in the liver are associated with
high-output cardiac failure due to increased vascular flow.
most common causes of meningitis in neonatal period
Group B Strep, E coli, and Listeria
most common cause of brain abscess formation in meningitis (babies)
citrobacter koseri or freundii
Spinal motor atrophy type I
Wednig Hoffman disease
progressive denerative disease of motor neurons
feeding difficulties, progressive hypotonia, weakness, absent DTR, tongue fasciculations, respiratory distress
confirm with muscle biopsy; simplest dx is SMN gene mutation in blood
most serious possible complication of chicken pox?
2nd most common acute vasculitis in kids and most common cause of acquired heart disease
dx: fever 5 days, plus 4/5:
intraoral erythema and/or dry, cracked lips
extremity edema and erythema
rash of any type except vesicular
almost always a single, tender, large anterior cervical node
admit, give IVIG and high dose aspirin
infant at high risk for RSV, treat with what?
palivizumab- up to 5 monthly intramuscular injections during RSV season
preemies, heart disease, etc.
most common cause of congenital hypothyroidism
finding with A fib?
enlarged left atrium
a fib can be from hyperthyroidism
retinoblastoma goes with
sickle cell and spleen
autoinfarction by around age 5
nitro blue test goes with
leukocyte adhesion deficiency
immunodeficiency that goes with neisseria
transfusion reaction goes with what immunodeficiency?
eczema and bleeding?
treat salicylate poisoning?
gastric lavage with airway protection
aggressive IV fluids with bicarb
sensorineural hearing loss
ALL signs/ symptoms
bone and joint pain lower extremities
anemia, thrombocytopenia, bleeding, fever, infecttion
organ infiltration: lymphadenopathy, hepatosplenomegaly, testicular enlargement, CNS involement
WBC can be normal or changed
fever first, then widespread macular rash 1-3 days.
looks like measles but ffades after 3 days. Posterior lymphadenopathy , sometimes arthralgias of hands
Syaphylococcal scalded skin syndrome
from an infectious nidus
toxin cleaves desmoglein-1
fever, conjunctivitis, diffuse rash, desquamation, nikolsky sign, radial crusting and fissuring around eyes, nose and mouth
Similar to bullous impetigo (exfoliative toxin-A)
maternal diabetes -->
neural tube, cardiac and urological malformations
treatment of ankylosing spondylitis
NSAIDs like indomethacin
TNF for advanced disease
discharge and odor, not STD.
grayish-white with pH over 4.5
KOH whiff test positive
clue cells (adherence of Gardnerella to epithelial cells)
treat with metronidazole
lack of platelet membrain GPIIB-IIIa --> bad aggregation
defective clot formation, bleeding esp from mucosal surfaces
Bell palsy associations
give glucocorticoids and eye lubricants
presentation of lice
itching of scalp
small, oval, whitish nodules firmly attached to hair shafts
scratching--> lichenification and posterior lymphadenopathy
treat with lindane, malathion, or permethrin
treatment of syphilitic chancre
painless with indurated edge. primary syphilis
benzathine pen G IM
likely Hep A. Test IgM in serum.
risk for subluxation of hips? (developmental dysplasia of the hip)
breech and female, family history
valproate exposure in utero -->
high broad forehead, epicanthal folds, thin, arched wide-spaced eyebrows, broad and low nasal bridge with a small upturned nose, thick lips
CV: septal defects, pulmonary atresia, coarctation of the aorta, aortic stenosis, hypoplastic left heart
cleft lip and palate
neural tube defects
developmental delays, ADD, communication problems, learning disorders
best test for lupus?
seizure is a common neurologic manifestation
most common cause of diffuse bronchiectasis in children
repeated doses of cefaclor can -->
serum sickness-like reaction
urticarial to purpuric rash, lymphadenopathy, fever, arthritis
periventricular white matter necrosis -->
cerebral palsy --> diplegic or quadriplegic spasticity