Key Associations Part 1 Flashcards Preview

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Flashcards in Key Associations Part 1 Deck (60):
1

Actinic keratosis

Precursor to squamous cell carcinoma

2

Acute gastric ulcer associated w/ CNS injury

Cushing ulcer (increased intracranial pressure stimulates vagal gastric secretion)

3

Acute gastric ulcer associated with severe burns

Curling ulcer (greatly reduced plasma volume results in sloughing of gastric mucosa)

4

Alternating areas of transmural inflammation and normal colon

Skip lesions (Crohn disease)

5

Aneurysm, dissecting

HTN

6

Aortic aneurysm, abdominal and descending aorta

Atherosclerosis

7

Aortic aneurysm, arch

tertiary syphilis (syphilic aortitis), vasa vasorum destruction

8

Aortic aneurysm, ascending

Marfan syndrome (idiopathic cystic medial degeneration)

9

Atrophy of the mammillary bodies

Wenicke encephalopathy (thiamine deficiency causing ataxia, opthalmoplegia, and confusion)

10

Autosplenectomy (fibrosis and shrinkage)

Sickle cell anemia (Hb S)

11

Bacteria associated with gastritis, peptic ulcer disease, and stomach cancer

H. pylori

12

Bacterial meningitis (adults and elderly)

Streptococcus pneumoniae

13

Bacterial meningitis (newborns and kids)

Group B streptococcus/E coli (newborns), S pneumoniae/N meningitidis (kids)

14

Benign melanocytic nevus

Spitz nevus (most common in 1st two decades)

15

Bleeding disorder with GpIb deficiency

Bernard-Soulier syndrome (defect in platelet adhesion to von Willebrand factor)

16

Brain tumor (adults)

Supratentorial: metastasis > astrocytoma (including glioblastoma multiforme) > meningioma > schwannoma

17

Brain tumor (kids)

Infratentorial: medulloblastoma (cerebellum) or supratentorial: craniopharyngioma

18

Breast cancer

infiltrating ductal carcinoma

19

Breast mass

Fibrocystic change, carcinoma (in post menopausal women)

20

Breast tumor (benign)

Fibroadenoma

21

Cardiac primary tumor (kids)

Rhabdomyoma, often seen in tuberous sclerosis

22

Cardiac manifestation of lupus

Libman-Sacks endocarditis (non bacterial, affecting both sides of mitral valve)

23

Cardiac tumor (adults)

Metastasis, primary myxoma (4:1 left to right atrium; "ball and valve"

24

Cerebellar tonsillar herniation

Chiari II malformation

25

Chronic arrhythmia

Atrial fibrillation (associated with high risk of emboli)

26

Chronic atrophic gastritis (autoimmune)

Predisposition to gastric carcinoma (can also cause pernicious anemia)

27

Clear cell adenocarcinoma of the vagina

DES exposure in utero

28

Compression fracture

Osteoporosis (type I: postmenopausal woman; type 2: elderly man or woman)

29

Congenital adrenal hyperplasia, hypotension

21-hydroxylase deficiency

30

Congenital cardiac anomaly

VSD

31

Congenital conjugated hyperbilirubinemia (black liver)

Dubin-Johnson syndrome (inability of hepatocytes to secrete conjugated bilirubin into bile)

32

Constrictive pericarditis

TB (developing world); SLE (developed world)

33

Coronary artery involved in thrombosis

LAD > RCA > LCA

34

Cretinism

Iodine deficit/hypothyroidism

35

Cushing syndrome

Iatrogenic cushing (corticosteroid therapy), adrenocortical adenoma (secretes excess cortisol), ACTH secreting pituitary adenoma, Paraneoplastic cushing (due to ACTH secretion by tumors)

36

Cyanosis (early, less common)

Tetralogy of Fallot, transposition of great vessels, truncus arteriosus

37

Cyanosis (late, more common)

VSD, ASD, PDA

38

Death in CML

Blast crisis

39

Death in SLE

Lupus nephropathy

40

Dementia

Alzheimer disease, multiple infarcts

41

Demyelinating disease in young women

Multiple sclerosis

42

DIC

severe sepsis, obstetric complications, cancer, burns, trauma, major surgery

43

Dietary deficit

Iron

44

Diverticulum in pharynx

Zenker diverticulum (diagnosed by barium swallow)

45

Ejection click

Aortic/pulmonic stenosis

46

Esophageal cancer

Squamous cell carcinoma (worldwide); adenocarcinoma (US)

47

Food poisoning (exotoxin mediated)

S aureus, B cereus

48

Glomerulonephritis (adults)

Berger disease (IgA nephropathy)

49

Gynecologic malignancy

Endometrial carcinoma (most common in US); cervical carcinoma (most common worldwide)

50

Heart murmur, congenital

Mitral valve prolapse

51

Heart valve in bacterial endocarditis

Mitral > aortic (rheumatic fever), tricuspid (IV drug abuse)

52

Helminth infection (US)

Enterobius vermicularis, Ascaris lumbricoides

53

Hematoma--epidural

Rupture of middle meningeal artery (trauma; lentiform shaped)

54

Hematoma--subdural

Rupture of bridging veins (crescent shaped)

55

Hemochromatosis

Multiple blood transfusions or hereditary HFE mutation (can result in CHF, "bronze diabetes", and increased risk of hepatocellular carcinoma)

56

Hepatocellular carcinoma

Cirrhotic liver (associated with Hep B and C and with alcoholism)

57

Hereditary bleeding disorder

von Willebrand disease

58

Hereditary harmless jaundice

Gilbert syndrome (benign congenital unconjugated hyperbilirubinemia)

59

HLA B27

Ankylosing spondylitis, reactive arthritis, ulcerative colitis, psoriatic arthritis

60

HLA-DR3 or DR4

Diabetes mellitus type 1, rheumatoid arthritis, SLE