KIDNEY FUNCTION TEST part 4 Flashcards
This measures the changes in NADPH to NAD+
F. Lim: Creatininase or creatinine iminohydrolase
This uses hydrogen peroxide method and measures the formation of color as benzoquinonemine dye forms.
Creatininase
This is the accepted reference method for the detection of characteristics using isotopically labeled compound.
IDMS
Under Yatzidis method, Protein & other interfering materials react w/ alkaline picrate but creatinine does not. What pH is this?
pH 10
Under Yatzidis method, Both creatinine & proteins react. What pH does this happen?
pH 11
This test provides a reasonable approximation of glomerular filtration rate (GFR).
Creatinine Clearance Test
What is the formula for Creatinine Clearance Test?
U x V/ P
What is the unit of Creatinine Clearance Test?
mL/minute
What is the relationship of plasma creatinine to creatinine clearance?
Inversely proportional
> 50% renal dysfunction = ____________________
abnormal plasma creatinine
Increased conversion of creatine into creatinine
Increased rate of Creatine Turnover
What is the reference range of Plasma/ Serum in Jaffe in females and males?
Female: 0.6- 1.1mg/dL
Male : 0.9- 1.3mg/dL
What is the reference range of Plasma/ Serum in Enzymatic in female and male?
Female 0.5- 0.8mg/dL
Male 0.6- 1.1mg/dL
What is the reference range of 24 hrs urine in female and male?
Female
600 - 1800mg/day
5.3 - 15.9 mmol/day
Male
800 - 2000mg/day
7.1 -17.7 mmol/day
This is the End-product of purine metabolism in humans and the major product of the catabolism of purine nucleosides.
BUA
