L2: Bleeding Disorders - Intro & Vascular Purpura Flashcards

(45 cards)

1
Q

Def of Hemostasis

A

It’s the capacity to minimize loss oof blood following injury to a blood vessel.

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2
Q

Hemostasis Depends on …..

A
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3
Q

Etiology of Bleeding Disorders

A
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4
Q

Etiology of Bleeding Disorders

  • Vascular
A
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5
Q

Etiology of Bleeding Disorders

  • Platlets
A
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6
Q

Etiology of Bleeding Disorders

  • Coagulation
A
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7
Q

General CP of Bleeding Disorders

A
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8
Q

General CP of Bleeding Disorders

  • External Bleeding
A
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9
Q

General CP of Bleeding Disorders

  • Internal Bleeding
A
  • Intracranial
  • intra abdominal
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10
Q

General CP of Bleeding Disorders

  • Cutaneous Bleeding
A
  • Petechiae
  • Ecchymosis
  • Purpura
  • Hematoma
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11
Q

Compare Between Petechiae & Ecchymosis in Terms of

  • Characters
  • Site
  • Size
  • Surface
  • Color
  • Causes
A
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12
Q

Etiology of Vascular Purpura

A
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13
Q

Etiology of Vascular Purpura

  • Acquired
A
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14
Q

Etiology of Vascular Purpura

  • Congenital
A
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15
Q

Characters of Scurvy

A
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16
Q

TTT of Scurvy

A

Vit. C (200-500 mg/day oral)

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17
Q

Causes of Steroid Prupura

A
  • Prolonged use of steroids → thinning of blood vessel wall
  • Increased Endogenous steroids “e.g. Cushing syndrome”
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18
Q

Mechanism of Traumatic Asphyxic Purpura

A

Increased intra capillary pressure → rupture of blood vessels.

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19
Q

Examples of Traumatic Asphyxic Purpura

A
  • Crushing injuries of the thorax
  • Epileptic fits
  • Severe chronic cough (as Whooping cough)
20
Q

Def of Anaphylactoid Purpura (HSP)

A
  • Small blood vesselsallergic vasculitis similar to rheumatic fever.
21
Q

Incidence of Anaphylactoid Purpura (HSP)

A
  • The most common cause of non thrombocytopenic purpura in children
22
Q

Age of Anaphylactoid Purpura (HSP)

23
Q

Sex in Anaphylactoid Purpura (HSP)

A

Male > Female (2:1)

24
Q

Etiology of Anaphylactoid Purpura (HSP)

25
CP of **Anaphylactoid Purpura (HSP)**
26
CP of **Anaphylactoid Purpura (HSP)** - Skin
27
CP of **Anaphylactoid Purpura (HSP)** - Joint
**Joint (75%):** Migratory polyarthritis
28
CP of **Anaphylactoid Purpura (HSP)** - GIT
**GIT (50%):** - Acute abdominal pain - diarrhea - bloody stool
29
CP of **Anaphylactoid Purpura (HSP)** - Renal
30
Complications of **Anaphylactoid Purpura (HSP)**
31
INVx for **Anaphylactoid Purpura (HSP)**
32
INVx for **Anaphylactoid Purpura (HSP)** - Bleeding Time
Normal
33
INVx for **Anaphylactoid Purpura (HSP)** - Clotting Time
Normal
34
INVx for **Anaphylactoid Purpura (HSP)** - Hiss Test
+ve
35
INVx for **Anaphylactoid Purpura (HSP)** - ASO
Increased
36
INVx for **Anaphylactoid Purpura (HSP)** - Serum IgA
Increased
37
INVx for **Anaphylactoid Purpura (HSP)** - Stool Analysis
For occult blood
38
INVx for **Anaphylactoid Purpura (HSP)** - Urine Analysis
For renal affection
39
INVx for **Anaphylactoid Purpura (HSP)** - Skin Biopsy
Vasculitis - IgA deposition **"Definite diagnosis"**
40
TTT of **Anaphylactoid Purpura (HSP)**
41
TTT of **Anaphylactoid Purpura (HSP)** - Penicillin
42
TTT of **Anaphylactoid Purpura (HSP)** - For Arthritis
Acetyl salicylic acid (Aspirin) "as for rheumatic arthritis".
43
TTT of **Anaphylactoid Purpura (HSP)** - For GIT Affection
Corticosteroids: Prednisone (1-2mg/kg/day oral).
44
TTT of **Anaphylactoid Purpura (HSP)** - For Renal Affection
Immune suppressive drugs as: - Cyclophosphamide (Endoxan) - Azathioprine (Imuran)
45
Medical Causes of **Acute Abdomen**