L9_Dynamics of the Host-Parasite Relationship Flashcards Preview

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Flashcards in L9_Dynamics of the Host-Parasite Relationship Deck (18):
1

Our relationship with most of our normal flora is best described as?

Commensalism

2

What are the most common skin commensals, which is the most dangerous opportunistic pathogen?

Staph epidermidis, Candida Albicans, and Staph Aureus. If not contained properly, staph aureus will cause disease (i.e. broken skin)

3

What does commensalism on the skin assume?

The skin is not broken

4

What does commensalism in the Respiratory Tract Assume?

The host is immunocompetent

5

What are the most common commensals in the Nose and Throat? Which species can cause problems if over grown?

Wide variety of commensals including Strep, Staph, and Nisseria. Problems with overgrowth of S. Pyogenes, N. Meningitidis, and S. Aureus

6

What commensal in the mouth can cause cavities and heart valve disease if hygiene is poor? Name two other commensals in the mouth

S. Mutans....Actinomyces (causes that buldge along the chin) and Kingella Kingae

7

Describe the colonization of the stomach, small intestine and large intestine.

Stomach usually free of bacteria, small intestine has strep, lactobacilli, and yeast, and the large intestine is totally full of a large variety which are mostly anaerobes (coliforms).

8

Name two examples of true symbiotes

Nutrient generating bacteria in gut and Lactobacillus in the vagina

9

How do commensals contribute to the innate immune system?

Colonization resistance

10

Describe the steps of Koch's Postulate.

Observe disease, culture pathogen, infect new host, observe same disease, culture same pathogen.

11

What does lactobacillus help do in the vagina?

Keep a low pH

12

What type of overgrowth can happen in vagina if pH rises?

Candida (yeast infection)

13

What is a danger to neonates from mothers commensals if delivered vaginally without antibiotics?

Group B strep (sepsis and Meningitis)
Also S. Aureus

14

Why is it difficult for most species to colonize on the skin?

Acid pH, Dry

15

List the chemical components of the innate immune system

Acid pH on skin, stomach, and vagina
lysozyme
Defensisns

16

List the microbiological component of the innate immune system

Colonization Resistance

17

List the Immunochemical components of the innate immune system

Fever, Interferon

18

List the Cellular components of the innate immune system

Macrophages and complement