Lab 2: Leukemia Flashcards Preview

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Flashcards in Lab 2: Leukemia Deck (31):
1

leukemia is part of what broader group of diseases

hematological neoplasms

2

rapid progression and accumulation of malignant cells, which then spill over into the bloodstream and spread to other organs

acute leukemia

3

most common forms of leukemia in children

acute leukemias

4

excessive build up of relatively mature, but still abnormal WBC

chronic leukemia

5

4 types of leukemia

ALL, CLL, AML, CML

6

cancerous change takes place in marrow cells that normally goes on to form B cell lymphocytes

lymphocytic or lymphoblastic leukemias

7

cancerous change takes place in marrow cells that normally go on to form RBCs, some WBCs, and platelets

myeloid or myelogenous leukemias

8

percentage of leukemias that are diagnosed in adults

90%

9

most common type of leukemia in young children

ALL

10

standard treatment of ALL and survival rates

chemotherapy and radiation. 85% in children, 50% in adults

11

leukemia that often affects adults over 55, 2/3 are men

CLL

12

incurable leukemia

CLL

13

survival rate of CLL

75%

14

uncommon hematological malignancy with the accumulation of abnormal B lymphocytes

Hairy cell leukemia

15

hairy cell leukemia is a subtype of which leukemia

CLL

16

occurs more commonly in adults than in children, more commonly in men than women. survival rate is 40%

AML

17

occur mainly in adults. survival rate is 90%

CML

18

term for pinprick bleeds

petechiae

19

2 symptoms caused by anemia

dyspnea and pallor

20

term for low platelets and what is causes

thrombocytopenia, bleeding in the eyes

21

what causes patients with leukemia to feel nauseated or full

enlarged liver and spleen

22

less-common condition where the cancerous cells remain in the marrow instead of entering the bloodstream

aleukemia

23

type of DNA mutation that causes leukemias

somatic mutations

24

how do certain mutations produce leukemia

activating oncogenes or deactivating tumor suppressor genes

25

tobacco use increases risk of which leukemia

AML

26

retrovirus that causes leukemia and what type

Human T-lymphotropic virus (HTLV-1) causes adult T-cell leukemia

27

genetic condition that significantly increases risk of developing forms of acute leukemia

down syndrome

28

what is leukemia diagnosis usually based on?

repeated CBCs and bone marrow examination

29

what do blood chemistry test determine

degree of liver and kidney damage, or effects of chemotherapy on the patient

30

why does the american cancer society predict that at least one fifth of people with leukemia have not yet been diagnosed

the symptoms are vague, unspecific, and can refer to other diseases.

31

5 types of leukocytes

neutrophils, eosinophils, basophils, lymphocytes, monocytes