Lab Med 135-150 Flashcards Preview

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Flashcards in Lab Med 135-150 Deck (19)
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1
Q

What is cyclosporine?

A

Used in suppressing host vs. graft rejection –> immunosuppression

2
Q

What is cytochemical staining?

A

Staining of hemosiderin in bone marrow
The “gold standard” for iron status
High staining = iron overload

3
Q

What is dabigatran?

A

A direct thrombin inhibitor best used for Afib and VTE

4
Q

What is digoxin?

A

A cardiac glycoside with variable absorption

5
Q

What is dysfibrinogenemia?

A

Interferent with fibrin-polymerization

Indicator of severe liver disease

6
Q

What is ethanol? What is it’s PK?

A

CNS depressant

Zero-order

7
Q

What is ethosuximide?

A

Anti-absence-seizures

Readily absorbed in the GI tract

8
Q

What is euthyroid hyperthyroxinemia?

A

High total thyroid hormone concentration with normal free concentrations
Normal thyroid function

9
Q

What is euthyroid hypothyroxinemia?

A

Low total thyroid hormone, normal free

Normal thyroid function

10
Q

What is Gilbert’s syndrome?

A

Transport and conjugation of bilirubin defect

11
Q

What is Grave’s disease?

A

Autoimmune hyperthyroidism with diffuse goiter

12
Q

What is hCG?

A

Human Chorionic Gonadotropin

13
Q

What is hemochromatosis?

A

Iron overload with tissue injury

14
Q

What is hemoglobin A2?

A

Functionally similar to Hgb A but higher O2 affinity

Elevated in diagnosis of beta-thalassemia

15
Q

What is hemoglobin F?

A

Higher O2 affinity than Hgb A

Elevated in patients with abnormal beta chain synthesis

16
Q

How does ethanol affect the osmolar gap?

A

Increase

17
Q

Where is HcG found?

A

Serum

Urine

18
Q

What is hCG used for?

A

Monitoring clinical management of non-seminomatous germ cell tumor of the testes, choriocarcinoma, and hydatidiform mole

19
Q

What lab values do you see with hemochromatosis?

A

Low transferrin

Low TIBC