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Lab Medicine > Lab Med 76-90 > Flashcards

Lab Med 76-90 Flashcards

1
Q

What are tumor markers used for?

A

Detection of recurrence and monitoring of therapy

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2
Q

What can cause a decrease in lymphocytes?

A

Steroids

Immune deficiency

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3
Q

What can cause a decrease in neutrophils?

A

Myelodysplasia

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4
Q

What can cause a decrease in platelets?

A

Thrombocytopenic purpura - idiopathic & thrombotic
bone marrow failure
disseminated IV coag

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5
Q

What can cause a decrease in WBCs?

A

Aplastic anemia
Hypoplastic anemia
Myelofibrosis

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6
Q

What can cause a rise in ALP?

A

A compromised biliary tract lining (due to inflammation, necrosis, obstruction)

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7
Q

What can cause a rise in WBCs?

A

Infection

Inflammation

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8
Q

What can cause an elevation in both conjugated and unconjugated bilirubin? (9)

A 
Biliary obstruction/flow obstruction  
Hepatitis, 
cirrhosis, 
post-hepatic obstruction, 
Dubin-Johnson, 
BC 
pregnancy
Rotor's, 
drug-induced cholestasis
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9
Q

What can cause an elevation in conjugated bilirubin with a minor increase in unconjugated bilirubin?

A

Early cholestasis - usually transient with day to day fluctuation

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10
Q

What can cause an increase in lymphocytes?

A

Viral infections

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11
Q

What can cause an increase in neutrophils?

A

Steroids
Inflammation
Leukemia
Bacterial infection

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12
Q

What can cause an increase in platelets?

A

Inflammation

Disseminated cancer

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13
Q

What can cause euthyroid hyperthyroxinemia?

A

Increase in thyroid hormone binding

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14
Q

What can cause euthyroid hypothyroxinemia?

A 
Decrease in thyroid hormone binding  
Systemic illness (sick euthyroid syndrome) 
Stress Surgery (decreases T3) 
Starvation/fasting (decreases T3) 
Decrease in TBG
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15
Q

What can cause iron deficiency in children

A

Dietary deficiency

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16
Q

How are the increases in ALP classified?

A

< 3 times normal = hepatocellular damage

>3 times normal = post-hepatic obstruction

17
Q

What can cause iron deficiency in adults?

A

large blood loss

Lab Medicine (23 decks)

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