Lab: Toothpaste

Question 1

“powder for rubbing the teeth”

Answer 1

-Dentrificum

Question 2

fricare

Answer 2

to rub

Question 3

Dentis

Answer 3

tooth

Question 4

-Agent used with a toothbrush to clean and polish the accessible
surfaces of the teeth

Answer 4

TOOTHPASTE

Question 5

TOOTHPASTE forms

Answer 5

paste, powder, gel or liquid

Question 6

T/F: Liquid form is different from mouthwash

Answer 6

True

Question 7

Most important toothpaste form

Answer 7

paste

Question 8

It is the preferred dosage vehicle for special therapeutic
and cosmetic agents due to its rheological properties in the
form of paste.

Answer 8

Paste form

Question 9

It has
an occlusive property unlike powders or liquids that are
easily washed off by the saliva

Answer 9

Paste form

Question 10

-Liquid form is not __________

Answer 10

abrasive

Question 11

a biofilm or mass of bacteria that grows
on surfaces within the mouth.

Answer 11

Dental plaque

Question 12

also known as
tartar

Answer 12

into dental calculus

Question 13

TOOTHPASTE COMPOSITION

Answer 13

Abrasive
Foaming Agents
Flavoring Agents
Sweetening Agents
Humectant
Binder/Gelling Agent/Thickener
Coloring Agent
Preservative
Special Additives

Question 14

-Particle size is largely below 0.4 mm in diameter

Answer 14

Abrasive

Question 15

Titanium dioxide
Insoluble phosphate, Dicalcium phosphate (dihydrate and anhydrous), calcium phosphate
Sodium bicarbonate (baking soda)
Calcium carbonate (Precipitated chalk)
Hydrated silica
Silicon oxide, aluminum oxide, granular polyvinyl chloride

Answer 15

Abrasive

Question 16

-Typical dentifrices which have significant consumer acceptability
are the toothpaste having a high content of____________ abrasive
such as: __________ and ________

Answer 16

water-insoluble;
● Dicalcium phosphate
● Sodium monofluorophosphate 0.2% in aqueous humectant
base

Question 17

● sodium lauryl sulfate(SLS),
● sodium dodecylbenzene sulfonate,
● magnesium lauryl sulfate,
● sodium lauryl sulfoacetate,
● dioctyl sulfosuccinate, and
● sodium coconut monoglyceride sulfonate

Answer 17

Surfactant

Question 18

peppermint, spearmint, wintergreen, cinnamon, mint,
thymol, menthol, clove oil, eucalyptol oil

Answer 18

flavoring agent

Question 19

Leave a residual freshness and cooling sensation

Answer 19

Flavoring agent

Question 20

-Sweetens the taste
-Non fermentable sugar

Answer 20

Sweetening agent

Question 21

sodium saccharin (most widely used),
sorbitol, mannitol, glycerin, acesulfame,
aspartame

Answer 21

Sweetening agent

Question 22

-Maintain moisture and consistency of paste by absorbing moisture
from air

Answer 22

HUMECTANT

Question 23

-Provides creamy base which resists drying out

Answer 23

HUMECTANT

Question 24

-Vehicle where other ingredients can be suspended or dissolved

Answer 24

HUMECTANT

Question 25

5 to 35%of total vehicle

Answer 25

HUMECTANT

Question 26

E.g. glycerol, 70% sorbitol, PG, PEG, mannitol

Answer 26

HUMECTANT

Question 27

-Maintains the PASTY consistency of the preparation

Answer 27

BINDER/ GELLING AGENT/ THICKENER

Question 28

Develops a cohesive structure with desired rheological properties

Answer 28

BINDER/ GELLING AGENT/ THICKENER

Question 29

hydrophilic colloids that disperse and swell in the water phase

Answer 29

BINDER/ GELLING AGENT/ THICKENER

Question 30

● synthetic cellulose derivatives (CMC, MC,HEC) ● alginates, such as sodium alginate; ● gums, such as xanthan gum;tragacanth ● carrageenan or calcium carrageenate ● carbomer; ● polyacrylates, clays (both natural processed bentonite and synthetic clays). ● Precipitated silica

Answer 30

BINDER/ GELLING AGENT/ THICKENER

Question 31

Titanium dioxide, mica

Answer 31

Coloring agent

Question 32

-Toothpaste without _____________ are formulated with preservatives (approx. 0.2% w/w) to prevent bacterial growth for long term storage

Answer 32

ionic surfactants

Question 33

sodium benzoate, dichlorophene, ethyl and methyl paraben; formaldehyde

Answer 33

PRESERVATIVE

Question 34

Low abrasive level / High humectant level

Answer 34

Type I Toothpaste

Question 35

High abrasive level / Low humectant level

Answer 35

Type II Toothpaste

Question 36

-Ribbon of substantial thickness

Question 37

Toothpaste _______ (does not penetrate/penetrates) -substantially into the bristle of the brush upon standing

Answer 37

does not penetrate

Question 38

Toothpaste ________ (does not form/ forms) a string when finger is pulled away from ribbon

Answer 38

does not form

Question 39

T/F: -Rheological properties affect aesthetic and functional attributes

Answer 39

True

Question 40

-Ideal rheological profile:

Answer 40

● Rigid gelatinous structure ● Becomes deformed and flowable with application of minimal stress ● Reestablishes its original structure almost instantaneously

Question 41

QUALITY PARAMETERS

Answer 41

1.Spreadability 2.Extrudability 3.Foaming property 4.Flavor 5. Preservative Efficacy 6.Viscosity 7.Color 8.pH

Question 42

EFFICACY (PERFORMANCE) PARAMETERS

Answer 42

1.Antimicrobial activity 2.Whitening activity -If the product claims to have a whitening effect 3.Hypersensitivity reduction -If the product claims to be for sensitive teeth