Laboratory Findings Flashcards
(104 cards)
1
Q
antinuclear antibodies
A
SLE
2
Q
antiplatelet antibodies
A
idiopathic thrombocytopenic purpura
3
Q
anti topoisomerase antibodies
A
diffuse systemic sclerderma
4
Q
anti transglutaminase/anti-gliadin/anti-endomysial antibodies
A
celiac disease
5
Q
atypical lymphocytes
A
EBV
6
Q
azurophilic peroxidase positive granular inclusions in granulocytes and myeloblasts
A
Auer rods (AML)
7
Q
bacitracin response
A
GAS
8
Q
bamboo spine on xray
A
ankylosing spondylitis
9
Q
basophilic nuclear remnants in RBC
A
Howell-Jolly bodies due to splenectomy or nonfunctional spleen
10
Q
basophilic stippling of RBC
A
lead poisoning or sideroblastic anemia
11
Q
bloody or yellow tap on lumbar puncture
A
subarachnoid hemorrhage
12
Q
boot-shaped heart on x-ray
A
tetralogy of fallot
13
Q
branching gram positive rods with sulfur granules
A
actinomyces israelii
14
Q
bronchogenic apical lung tumor on imaging
A
pancoast tumor
15
Q
brown tumor of bone
A
hyperparathyroidism or osteitis fibrosa cystica
16
Q
cardiomegaly with atypical atrophy
A
chagas disease
17
Q
cellular crescents in Bowman capsule
A
rapidly progressive crescentic gomerulonephritis
18
Q
chocolate cyst of ovary
A
endometriosis
19
Q
circular grouping of dark tumor cells surrounding pale neurofibrils
A
Homer Wright rosettes (neuroblastoma, medulloblastoma)
20
Q
colonies of mucoid pseudomonas in lungs
A
cystic fibrosis
21
Q
decrease in AFP in amniotic fluid/maternal serum
A
Down syndrome
22
Q
degeneration of dorsal column fibers
A
tabes dorsalis, subacute combined degeneration
23
Q
delta wave on EKG, short PR interval, supraventricular tachycardia
A
Wolf-Parkinson-White syndrome
24
Q
depigmentation of neurons in substantia nigra
A
Parkinson disease
25
desquamated epithelium casts in sputum
Curschmann spirals (bronchial asthma)
26
disarrayed granulosa cells arranged around collections of eosinophilic fluid
Call-Exner bodies (granulosa cell tumor of the ovary)
27
dysplastic squamous cervical cells with raisinoid nuclei and hyperchromasia
Koilocytes (HPV-predisposes to cervical cancer)
28
electrical alternans
pericardial tamponade
29
enlarged cells with intranuclear inclusion bodies
owl eye appearance of CMV
30
enlarged thyroid cells with ground-glass nuclei with central clearing
Orphan Annie eyes nuclei (papillary carcinoma of the thyroid)
31
eosinophilic cytoplasmic inclusion in liver cell
mallory body (alcoholic liver disease)
32
eosinophilic cytoplasmic inclusion in nerve cell
Lewy body (parkinson disease)
33
eosinophilic globule in liver
councilman body (viral heptatitis, yellow fever), represents hepatocyte undergoing apoptosis
34
eosinophilic inclusion bodies in cytoplasm of hippocampal and cerebellar neurons
Negri bodies of rabies
35
extracellular amyloid deposition in gray matter of brain
senile plaques (Alzheimer disease)
36
giant B cells with bilobed nuclei with prominent inclusions
Reed Sternberg cells (Hodgkin lymphoma)
37
glomerulus like structure surrounding vessel in germ cells
Schiller-Duval bodies (yolk sac tumor)
38
hair on end crew cut appearance on x-ray
beta thalassemia, sickle cell disease
39
hCG elevated
choriocarcinoma, hydatidiform mole (occurs with and without embryo and multiple pregnancy)
40
heart nodules (granulomatous)
aschoff bodies (rheumatic fever)
41
heterophile antibodies
infectious mononucleosis
42
hexagonal, double pointed, needle like crystals in bronchial secretion
bronchial asthma (Charcot-Leyden crystals: eosinophilic granules)
43
high levels of D-dimers
DVT, PE, DIC
44
hilar lymphadenopathy, peripheral granulomatous lesion in middle or lower lung lobes
Ghon complex
45
honeycomb lung on xray or CT
interstitial pulmonary fibrosis
46
hypercoagulability leading to DVTs and vasculitis
Trousseau syndrome (adenocarcinoma of pancreas or lung)
47
hypersegmented neutrophils
megablastic anemia (B12 deficiency has neuro, folate no neuro symptoms)
48
hypertension, hypokalemia, metabolic alkalosis
conn syndrome (primary hyperaldosteronism)
49
hypochromic, microcytic anemia
iron deficiency anemia, lead poisoning, thalassemia
50
increased AFP in amniotic fluid/maternal serum
dating error, anencephaly, spina bifida (neural tube defect)
51
increased uric acid levels
gout, Lesh-Nyhan syndrome, tumor lysis syndrome, loop and thiazide diuretics
52
intranucelar eosinophilic droplet like bodies
Cowdry type A bodies
53
iron containing nodules in alveolar septum
ferruginous bodies (asbestosis)
54
keratin pearls on skin biopsy
squamous cell carcinoma
55
large granules in phagocytes, immunodeficiency
Chediak-Higashi disease
56
lead pipe appearance of colon on abdominal imaging
ulcerative colitis (loss of haustra)
57
linear appearance of IgG deposition on glomerular and alveolar basement membranes
Goodpasture syndrome
58
low serum ceruloplasmin
Wilson disease (hepatolenticular degeneration)
59
lumpy bumpy appearance of glomeruli on immunofluorescence
poststrep glomerulonephriits
60
lytic punched out bone lesions on xray
multiple myeloma
61
mammary gland (blue domed) cyst
fibrocystic change of the breast
62
monoclonal antibody spike
multiple myeloma
MUGS
waldenstrom macroglobulinemia
primary amyloidosis
63
mucin filled cell with peripheral nucleus
signet ring-gastric carcinoma
64
narrowing of bowel lumen on barium x-ray
string sign-Crohn disease
65
necrotizing vasculitis (lungs) and necrotizing glomerulonephritis
granulomatosis with polyangiitis and goodpasture syndrome
66
needle shaped, negatively birefringent crystals
gout
67
nodular hyaline deposits in glomeruli
Kimmelstiel-Wilson nodules (diabetic nephropathy)
68
novobiocin response
staph epidermidis sensitive
69
nutmeg appearance of liver
chronic passive ongestion of liver due to RHF or Budd-Chiari syndrome
70
onion skin periosteal reaction
Ewing sarcoma (malignant small blue cell tumor)
71
optochin response
strep pneumo sensitive
72
periosteum raised from bone, creating triangular area
Codman triangle on x-ray, Ewing sarcoma, pyogenic osteomyelitis
73
podocyte fusion or effacement on electron microscopy
minimal change disease (child with nephrotic syndrome)
74
polished, ivory like appearance of bone at cartilage erosion
eburnation (osteoarthritis resulting in bony sclerosis)
75
protein aggregates in neurons from hyperphosphorylation of tau protein
neurofibrillary tangles (Alzheimer disease) and Pick bodies (Pick disease)
76
psammoma bodies
meningiomas, papillary thyroid carcinoma, mesothelioma, papillary serous carcinoma of the endometrium and ovary
77
pseudopalisading tumor cells on brain biopsy
gliobalstoma multiforme
78
RBC casts in urine
glomerulonephritis
79
rectangular, crystal like, cytoplasmic inclusions in Leydig cells
reinke crystals (Leydig cell tumor)
80
recurrent infections, eczema, thrombocytopenia
Wiskott-Aldrich syndrome
81
renal epithelial casts in urine
intrinsic renal failure
82
rhomboid crystals, positively birefringent
pseudogout
83
Rib notching
coarctation of the aorta
84
ring enhancing brain lesion in AIDS
toxoplasma gondii, CNS lymphoma
85
sheets of medium-sized lymphoid cells with scattered pale, tingible body-laden macrophages
Burkitt lymphoma
86
silver staining spherical aggregation of tau proteins in neurons
Pick bodies
87
soap bubble in femur or tibia on x-ray
giant cell tumor of bone
88
spikes on basement membrane, dome like subepithelial deposits
membranous nephropathy
89
stacks of RBCs
rouleaux formation (multiple myeloma)
90
steeple sign on chest xray
croup (parainfluenza)
91
stippled vaginal epithelial cells
clue cells (gardnerella vaginalis)
92
strep bovis bacteremia
colon cancer
93
tennis racket shaped cytoplasmic organelles in langerhans cells
Birbeck granules in langerhans cell histiocytosis
94
thousands of polyps on colonoscopy
FAP
95
thrombi made of white/red layers
lines of Zahn (arterial thrombus, layers of platelets/RBCs)
96
thumb sign on lateral neck x-ray
epiglottitis (h. flu)
97
thyroid like appearance of kidney
chronic pyelonephritis
98
tram track appearance of capillary loops of glomerular basement membranes on light microscopy
membranoproliferative glomerulonephritis
99
triglyceride accumulation in liver cell vacuoles
fatty liver disease (alcoholic or metabolic syndrome)
100
waxy casts with very low urine flow
chronic end-stage renal disease
101
WBC casts in urine
acute pyelonephritis
102
WBC look smudged
CLL (almost always B cell)
103
wire loop glomerular capillary appearance on light microscopy
diffuse proliferative glomerulonephritis
104
yellowish CSF
xanthochromia due to subarachnoid hemorrhage
