Language and Lateralization Flashcards

(39 cards)

1
Q

What function is the most understood to be lateralized in the human brain?

A

Language skills are lateralized, more so than any other brain process

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2
Q

Broca’s Area

A

Key in language processing

Appears to be involved in speech production

Broca’s aphasia = Damage causing difficulty in speech production

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3
Q

Wernicke’s Area

A

Important for language comprehension

Damage causes difficulty understanding language

e.g. vocalizations can be made, but grammar, syntax, and language use suffer greatly

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4
Q

Broca and Wernicke’s areas are both on the…

A

Left side

For right-handed individuals at least

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5
Q

No Aphasics…

A

Have damage restricted to JUST Broca’s or Wernicke’s area

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6
Q

Aphasics almost always have damage to…

A

Subcortical white matter

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7
Q

Which types of lesions are most likely to produce expressive symptoms?

A

Large anterior legions

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8
Q

Global aphasia is usually related to…

A

Massive lesions of across several regions

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9
Q

Aphasics sometimes have damage not enroaching innto broca/wernickes area. For example…

A

Maybe the Broca’s area is fine, there is damage in the white matter tracts

can no longer send information to next region causing speech production issues

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10
Q

Damasio’s PET study of naming

A
  • Images of famous faces, animals, and tools
  • Activity while judging image orientation subtracted from activity while naming
  • Left temporal areas activated by naming, beyond wernickes area
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11
Q

Electrical stimulation to cortex on language ability - Study

A
  • Left hemisphere of a 37-yr old epileptic
  • Number areas on brain where stimulation applied
  • Same study completed on monkey’s, same areas reported
  • Many sites where stimulation produces either complete arrest of speech or disrupted/not blocked completely
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12
Q

Is language learned or innate?

A

Both!

  • Some appear to be innate, some learned through experience
  • Same for many processes
  • Some inheritability/differences in ability to learn language
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13
Q

FOXP2

A
  • Specific gene, shown to be relevant to language development
  • Neanderthals shared this gene, monkeys do nott
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14
Q

FOXP2 and Mice

A

Mice with FOXP2 gene mutations do not evoke communicative ultrasonic vocalizations

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15
Q

FOXP2 and Birds

A

When FOXP2 expression is blocked, young male birds fail to learn and recite bird song

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16
Q

Suggestions of innate language ability

A
  • Many animals have some rudimentary communicative skills
  • Not the same as language (which requires a grammatical code)
  • Although, we are the ones who have defined language as requiring grammatical code, so it is by our definition that other organisms versions of communication do not meet threshold for language
17
Q

Song areas in birds

A
  • Very similar to the neural circuits for language area in humans
  • Similarities maintained in its rudimentary form
18
Q

The learned nature of language

A

we aren’t just born with the ability to converse

Takes time for us to develop language skills, most certainly happens through exposure

19
Q

Critical period

A

Period in development when exposure or practice must occur for skills to develop

20
Q

Example of a critical period

A

Visual processing

Plasticity of brain will reconnect a baby’s neurons from a blind eye, this the eye must be recovered quickly or normal sight will never be regained

21
Q

Sensitive period

A

A period in development when exposure or practice will most facilitate the development of skills

22
Q

Example of sensitive period

A

Social behaviour

An individual who experiences extreme stress as a child may show social deficits/abnormalities, these abnormalities can be overcome (sort of, sometimes)

23
Q

Sensitive period of language

A
  • Appear to be formed in early childhood to late adolescence (earlier and earlier)
  • Adults who try to learn a language have a much harder time
  • Most interestingly, they appear to learn language differently too!
24
Q

Comparison of adult/Child Bilinguilism

A
  • Specific area activating for native language 1&2, many overlap
  • Adult has much less overlap
  • Region in anterior temporal cortex appears to be active for language
  • Broca’s area, inferior temporal cortex
25
Cerebral Lateralization of Function - Left hemisphere
- Superior in controlling ipsilateral movement - An interpreter
26
Cerebral Lateralization of Function - Right Hemisphere
Superior in: - Spatial ability - Emotion - Musical ability - Some memory tasks
27
Lateralization of function - Is this how the brain works?
For many functions, there are no differences betweeen hemispheres Lateralization of function is statistical rather than absolute
28
Corpus Callosum - The Split Brain
- The largest cerebral commissure - Transfers learned information from one hemisphere to the other - When cut, each hemisphere functions independently
29
Myers and Sperry experiment breakdown
- Transected the corpus callosum and optic chaism so that visual information could not cross to the contralateral hemisphere - Blindfold one eye of the cats, restrict visual information to the hemisphere ipsilateral to the uncovered eye - Each hemisphere can learn independently
30
Myers and Sperry Experiment - Differences between split and intact brain cats
- Split-brain cats with one eye patches learn tasks as well as controls - Intact cats: Learning transfers between hemispheres - Learning is intact, switch eyes --> SPLIT cats need to learn all over again (each hemisphere is learning independently)
31
Commissurotomy in Human Epileptics
- May never have another major convulsion - Procedure to test split-brain patients - Differ from split-brain animals that the two hemispheres have different abilities, most left hemispheres are capable of speech, right not - Difference is really that humans have language capabilities that animals do not
32
What happens when you present a picture to the right visual visual field to split-brain patient?
(left brain) - Left hemisphere can tell you what the photo is - Right hand can show you, left cannot
33
What happens when you present a picture to the left visual visual field to split-brain patient?
(Right brain) - Subject will report they do not know what it is - Left hand can show you what it was, right hand cannot
34
Cross-Cuing
Facial feedback from other hemisphere Right hemisphere might make the face frown when the left incorrect spoken answer
35
Split-brain patients: Helping-hand phenomenon
Presented with two different visual stimuli, hand that "knows" may correct the other
36
Split-brain patients: dual foci of attention
Split-brain hemisphere's can search for target item in array faster than intact controls
37
Split-Brain patients: Chimeric figures task
Only symmetrical version of right half of faces recognizes indicates competition between hemispheres
38
Chimeric Figure Test
Left hemisphere of a split-brain pt. sees a single-normal face that is completed version of the face on the right, right hemisphere sees a single normal face that is completed on the left
39
z-Lens
Can be used to assess each hemisphere's understanding of spoken instructions by limiting visual information to one side of the brain