Late-Onset Neurodegeneration as an Inflammatory Disease Flashcards Preview

Developmental Genetics > Late-Onset Neurodegeneration as an Inflammatory Disease > Flashcards

Flashcards in Late-Onset Neurodegeneration as an Inflammatory Disease Deck (15):
1

What does the hypothesis state?

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2

Inflammation occurs when there is nerve cell death.
True or False?

- Correlations known for a long time.

3

What does the innate immune system do?

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4

Why do some cells die?

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5

What is the relationship between innate immune components and cell death? (e.g Toll Receptor and Spaetzle).

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6

What are alarmins?

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7

What are the acute and chronic phase of inflammation?

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8

What are the two types of cell death?

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9

What are containment strategies in innate surveillance?.

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10

Examples of cellular clearance mechanisms?

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11

Trigger molecules and PRRs in innate surveillance.

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12

What are some examples of trigger molecules and their PRRs?

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13

What are the autonomous and non-autonomous cell death responses of the innate surveillance?

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14

How can unfolded proteins contribute to inflammation?

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15

What is the genetic evidence for the causal role for innate immunity in nerve cell death?

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