Lec 15 Substrate Utilization Flashcards

1
Q

What is RER and how is it measured

A

Respiratory exchange ratio

Carbon dioxide produces / oxygen consumed

VCO2/VO2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Carbohydrate vs lipid as fuel

What is the RER if carbohydrates are the fuel

A

1.0

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Carbohydrate vs lipid as fuel

What is the RER if lipids are the fuel

A

0.71

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Carbohydrate vs lipid as fuel

What is the RER for a MIXED fuel

A

1.0< RER< 0.71

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

_____ % more energy per unit of O2 for _________ vs. ________

A

7.7%

For carbohydrates vs lipids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What does higher or lower RER mean

A

Show the intensity of exercise
Higher RER the higher the intensity

Show what type of fuel you are using

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the five factors that influence substrate oxidation

A

Exercise intensity, duration, sex, substrate availability, training status

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the main energy source at 60-65% of vo2max

A

Fat oxidation specifically plasma FF acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the main energy source above 60-65% of vo2max

A

Carbohydrate oxidation

Lipids are used sparingly especially when exercise intensity is greater than 65% of vo2max

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

As you increase exercise intensity especially over 65% of vo2max you will you more ?

A

Muscle glycogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

There are EXPONENTIAL INCREMENTS in muscle ___________ and ___________ as functions of relative exercise intensity

A

Glycolysis and glycogenolysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

There is a MULTI COMPONENT RESPONSE of ____________ and ____________ with different intensities of exercise

A

Plasma FFA and triglycerides utilization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

The maximal muscle triglyceride utilization occurs at _____ % of Vo2max

A

65 %

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

FFA oxidation is predicted to reach minimal values as _______ is approached

A

Vo2max

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Duration and substrate utilization

120 minutes at 25% vo2max

What is used

A

Long duration low intensity

No use of glycogen stores

Fats dominate especially plasma FFA (blood borne)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Duration and substrate utilization

120 minutes at 65% vo2max

What is used

A

At the beginning use muscle glycogen the most but at the end use plasma FFA the most to compensate

Muscle triglycerides get repeated over time and same with muscle glycogen

17
Q

What happens to pyruvate levels in a carb fed state

A

Increased blood lactate, blood glucose and pyruvate levels implying more glycolysis

18
Q

Glycogen content was higher in….?

A

Carb diet not mix diet or fat protein diet

19
Q

When comparing diets who could cycle the longest

Protein fat diet, mixed, carbs

A

Longest to shortest

Carb, mixed, protein + fat

20
Q

Cycling time was correlated with what

A

Initial glycogen content

21
Q

Glycogen content of the working muscle is a determinant of what

A

Of the capacity to perform long and heavy exercise

22
Q

What was the effect of fat + protein diet after exhaustive work

What about carbohydrate diet ?

A

Did not synthesize the muscles glycogen content to more than 30% of the initial value

Raised the concentration to far above normal range

23
Q

What is carb loading

A

Elevating pre exercise muscle glycogen content above normal resting values

24
Q

Carb loading

When does it have effects and no effects

A

Has effects in endurance events lasting more then 90 minutes
- can postpone fatigues be 20%
Exhaustion usually coincides with critically low muscle glycogen

Has NO effect
On high intensity exercise lasting less than 5 min and/or on moderate-low intensity exercise lasting. 60-90 mins
- in such exercise substantial quantities of glycogen remain in the working muscle at the end of exercise

25
Are RER levels higher in male or females
Males because they use more carbohydrates whereas females use more fats
26
Fat oxidation contribute to a higher percentage of energy production during exercise in what gender
Females
27
Training status and substrate usage Who uses more carbs/glycogen, who has a higher RER, who uses more FFA, who produces more lactate
Untrained Use more glycogen/ carbs, have a higher RER, produce more lactate Trained Use more FFA
28
When comparing trained endurance athlete to untrained Trained endurance athletes will
Perform the given task at a LOWER RELATIVE EXERCISE INTENSITY Derive a lower percentage of energy for carbohydrate fuel sources aka glycogen, glucose and lactate Drives a greater percentage of energy from lipid energy sources Aka plasma FFA and intramuscular triglycerides
29
What is the advantage of lipid oxidation What is the value of the difference
When comparing the unit WEIGHTS Lipid oxidation 9.1 kcal/g energy Carbohydrate 4.2 kcal/g energy Lipids produces 2.17 times/ unit of WEIGHT greater energy Note. Not comparing per unit of oxygen