Lec 15 Typhoid Fever Flashcards Preview

OS 217 Infectious Diseases > Lec 15 Typhoid Fever > Flashcards

Flashcards in Lec 15 Typhoid Fever Deck (18)
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1

Triad of typhoid fever

Fever, headache, GI disturbance

2

T/F: Presence of clinical symptoms characteristic of typhoid fever or the detection of a specific antibody response is definitive of typhoid fever.

F. Suggestive of typhoid fever but not definitive

Definitive lang pag may na isolate na S. typhi galing sa lesion or sa blood.

3

Gold standard for the diagnosis of typhoid fever.

Blood culture

4

Acute/Semi-acute/Convalescent Phase of Typhoid Fever?
IgM: +
IgG: -

Acute

5

Acute/Semi-acute/Convalescence Phase of Typhoid Fever?
IgM: -
IgG: +

Convalescence

6

Widely regarded as optimal for the treatment of typhoid fever in adults.

Fluoroquinolones

7

Given in complicated cases of typhoid fever, because it is an antibiotic with a relative long half life. Given once a day.

ceftriaxone IV.

8

Rate of carriage of S. typhi is higher among:
a. female patients,
b. patients older than 50 years
c. patients with cholelithiasis or schistosomiasis
d. AOTA
e. NOTA

d. AOTA

9

A cook for several well-to-do families, seemed a healthy person when a health inspector knocked on her door in
1907, yet she was in actuality the cause of several deadly typhoid outbreaks.

a. HIV Adre
b. Typhoid Mary
c. STD Ron
d. Septic Carlos

b. Typhoid Mary

10

S. typhi multiplies in:

Mononuclear phagocytic cells

11

Pathognomonic sign of Typhoid fever

Rose spots (exanthem)

12

Incubation period of S. typhi

8-14 days

13

This capsule provides the basis for one of the commercially available vaccines against S. typhi.

Polysaccharide capsule Vi

14

Fever lysis means patient has no fever for at least:

24 hours

15

Suspect typhoid if there is fever of more than:

7 days

16

Use of the 50 kD antigen to detect specific IgM and IgG
antibodies to S. typhi.

TYPHIDOT

17

MDR Strains of S. typhi have resistance to:

Chloramphenicol,
Ampicillin
Trimethoprim-sulfamethoxazole

18

T/F: Classic typhoid fever presents with absence of leukocytosis

T. Absence of leukocytosis is considered a criteria for typhoid. WBC count is normal or below normal. But, when patient presents with rising white blood cell count with a left shift and free air under the diaphragm on abdominal, consider intestinal perforation