Lec. 49 Fibrin Clot Flashcards
1
Q
How many coagulation factors and which is omitted?
A
There are 12
VI is omitted, so I to XIII
2
Q
Name all the coagulation factors and describe them.
A
Serine Proteases (zymogens): II (thrombin), VII, IX, X, XI, XII
Cofactor proteins: III (tissue factor), V, VIII
Calcium: IV
Fibrin: Ia (I is fibrinogen)
Transglutaminase (zymogen): XIII
3
Q
Where are the coagulation factors made and which can be stored?
A
Most are made in the liver and circulate freely in the blood.
Factors V and XIII can be taken up and stored in alpha-granules of platelets.
