Lec 6 Antigen Recognition, Processing, Presentation Flashcards Preview

Dental Microbiology > Lec 6 Antigen Recognition, Processing, Presentation > Flashcards

Flashcards in Lec 6 Antigen Recognition, Processing, Presentation Deck (20):
1

three antigen presenting cells

monocytes/macrophages, b cells, dendritic cells

2

dendritic cells present the antigen via blank

pinocytosis

3

cells that recognize antigen specifically

t cells, b cells

4

8-10 aa are recognized by blank

class 1

5

14-20 aa are recognized by blank

class 2

6

two types of t cells

cd4, cd8

7

cd4 t cells are blank t cells and recognize antigens in association with blank mhc molecules

helper, class 2

8

cd8 t cells are blank t cells and kill cells that present antigens. is a receptor for blank mhc molecules

cytotoxic, class 1

9

all cells of body present antigen to blank t cells

cd8

10

molecules which recognize a variety of structurally conserved molecules of microbes

TLRs

11

strong immunogens bind blank to mhc than weak immunogens

better

12

in the blank, class 1 and class 2 blank

segregate

13

class 1 goes directly to the blank after segregation

cell surface

14

class 2 goes to the blank after segregation

lysosomal like compartment

15

activation of a cd8 cell requires a blank secondary signal than those required for the activation of a cd4 cell

stronger

16

produced by pathogens ranging from bacteria to mammalian retroviruses

superantigens

17

superantigens bind to both mhc class blank molecules as well as tcr alpha beta simultaneously

2

18

superantigens stimulate most t cells that express a given blank sequence

alpha, beta

19

R: antigen recognition by blank cells is restricted by the blank so you cant take t cells from another person and expect them to work

t, mhc

20

R: know class 1 and class 2 inside and out

ok