*Lec 9-2 - Inflammation Modulators & Mechanisms Flashcards Preview

Dental Microbiology > *Lec 9-2 - Inflammation Modulators & Mechanisms > Flashcards

Flashcards in *Lec 9-2 - Inflammation Modulators & Mechanisms Deck (21):
1

sequence of inflammation

errythema, cytokine release (pain), cell endothelial cell activation, adhesion of leukocytes, edema

2

neuropeptides activate blank

mast cells

3

mitochondrial peptides, membrane phospholipids both activate blank

macrophages and dendritic cells and complement

4

TLR activation activates these

mast cells, neutrophils, macrophages

5

TNF alpha, IL17, IL1 are important because

clinicians focus on acting on these

6

TLR2 binds cell wall components of blank bacteria

gram negative

7

TLR4 binds cell wall components of blank bacteria

gram positive

8

cytokines and chemokines are secreted by blank in response to bacteria

macrophages/dendritic cells

9

IL 6 leads to blank

fever/acute protein production

10

tnf alpha leads to

fever and shock

11

IL 1 Beta leads to

fever production of IL6

12

these can also result in bacterial killing and tissue damage

fibroblasts

13

this part of cells has a reservoir of factors for cell proliferation, differentiation, activation, etc

extracellular matrix

14

leukocytes, chemokines are very important for blank

homing and where cells will go to

15

this is important for vascular permeability and muscle contraction

bradykinin

16

this is important for breaking down fibrin clots and activates complement

plasmin

17

fibrin causes blank

clots

18

this controls local acute inflammation and limits the inflammatory response

tgf beta

19

this has a big affect on lymphocytes

interferon gamma

20

interferon gamma, IL17 are both very involved in blank

inflammation

21

these produce IL17 and interferon gamma

Th17