Lec 9 Cell Cell Interactions Signaling & Activation Flashcards Preview

Dental Microbiology > Lec 9 Cell Cell Interactions Signaling & Activation > Flashcards

Flashcards in Lec 9 Cell Cell Interactions Signaling & Activation Deck (14):
1

best antigen presenting cells

dendritic

2

recognition by helper t cells requires macrophages and is restricted by the blank products

class 2 mhc

3

to get an immune response, both blank cells are required

T and B

4

the 2 signals required for b cell activation

one from antigen, one from t helper cell (usually cd40)

5

t and b cells cooperate and form a blank effect

synergistic

6

steps in b/t cell interactions

1. recognition of antigen by B cells via surface ig
2. b cell presentation to t cells
3. t cell secretion of cytokines which promote b cell growth/differentiation

7

icam stands for

cellular adhesion molecule

8

icams are on the surface to hold these together during interaction

t/b cells

9

central interaction of b and t cells occurs between these

TCR, MHC

10

ligand for TCR

MHC + antigen

11

activation of t cells is similar to b cells such as signaling cascades but the blank is different

antigen

12

Th1 and Th2 are blank cells

cytokine secreting

13

Th1 triggers blank response

cell mediated

14

Th2 triggers blank response

antibody mediated