Lecture 01: Introduction to Cardiac Pharmacology Flashcards
(16 cards)
how many deaths per year CVD
17.9 mill
31%
england 1 in 4 deaths evry 4 mins
from _____ rate of increase in life expectancy slowed
2011
2016
leading cause of death for men
second biggest cause of death for women
6.8 mill living with CVD
More common if
- male
- older
- severe mental illness
- ethnicity is south asian
- african caribbean
give the contrast man vs suffolk
Manchester (140.7 per 100,000)
Mid Suffolk (37.0 per 100,000) deaths 2016-17
what is NHS aim
prevent 150,000 strokes , hrt attacks and dementia cases over the next 10 yrs
Treatment effective at preventing cardiovascular events:
antihypertensives, statins, anticoagulants
problems with CVD prevention
- late diognosis
- under treatment
- deprived communities 30% more likely to have high BP
what is atrial fibrillation ?
-rapid, irregular heartbeat
- most common heart rhythm irregularity
- may cause blood clot formation
what fold does atrial fibrillation increase stroke risk by?
5
- 40 AF-related strokes every day in England
what % does anticoagulants reduce risk of stroke by ?
66%
what is the 2nd largest global risk factor for disease and disability ?
hypertension
12% of all visits to GP
further 5 mill have undetected high bp
what is high cholesterol characterised by?
build up of fatty deposits in arteries
1 in _ patients with ischaemic heart disease due to high cholesterol
3
what happens if Famillial Hypercholesterolaemia (FH) is left untreated
50% of men and 30% of women develop coronary heart disease by age 55
Management of FH with _____-lowering therapy with _____ is highly
effective
however most with FH remain ____
lipid
statins
undetected
