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Flashcards in lecture 1 Deck (48):
1

whole blood consists of

plasma (90% water, 10% dissolved salts)
serum - fluid part of blood after it has clotted which removes the fibrinogen

2

cellular components of blood include

RBC's, WBC's and platelets

3

where is hematopoiesis created in adults and prenatal animals

adults: bone marrow, liver and spleen in times of hematopoietic stress
prenatal: liver, spleen, thymus, and bone marrow

4

what is erthyropoiesis

production of RBC's

5

what is Leukopoiesis

production of WBCs

6

what is thrombopoiesis

production of platelets

7

what is the youngest type of RBC cell called

rubriblast

8

what is a mature RBC called

reticulocte

9

what happens to RBC's as they mature

overtime they get smaller and lose their nucleus, and also a change in collor

10

what is the youngest type of WBC cell called

myeloblast

11

what is the mature WBC called

segmented

12

what is the other name for thrombocytes and where are the derived from

platelets, and they come from megakaryocytes in the bone marrow via cytoplasmic demarcation

13

what is the function of RBC's

oxygen transport by hemoglobin

14

which species have nucleated RBC's

reptiles, amphibians, and birds

15

which species has the largest diameter for RBCs and what is it

dogs 7u

16

which species has the smallest diameter for RBC's and what is it

goats 4u

17

what is rouleaux

the stacking of RBCs

18

which species is it normal to have rouleaux in and less common in

horses - normal
rare in ruminants

19

when can rouleaux occur

when there is increased fibrinogen or globulin concentration in other species

20

what are agranulocytes

WBCs without granules

21

what are the 2 types of agranulocytes

lymphocytes, monocytes

22

what are the 3 types of granulocutes

neutrophils, eosinophils, basophils

23

what are granulocytes

WBC's with granules

24

where are neutrophils produced

in the bone marrow

25

how long do neutrophils circulate for

less than 24 hours

26

where do neutrophils migrate out of and go into what

out of the vessels and into tissues, alveoli, and gut lumen

27

segmented neutrophils are ____

polymorphonuclear

28

how many lobes can segmented neutrophils have

2 to 5 nuclear lobes

29

bovine neutrophils have what kind of cytoplasm

darker pink to orange

30

what do band neutrophils often look like

nuclear sides are parallel or nearly so and are smooth

31

what is a left shift

an increase of less mature neutrophils than segmented ones

32

what is a histogram

a graph for visulation of cell sizes and numbers

33

what is a supravital stain used for

staining reticulocytes

34

processing for blood serum what to do

allow sample to clot 20 to 30 min
2000 - 3000 rpm for 10 min

35

what are the collection sites for glucometer

marginal ear vein for cats, ear or footpad for dogs and cats

36

what are the 4 anticoagulants

1. EDTA, Heparin, Sodium Citrate, Potassium oxlate

37

what are platelets

anuclear cytoplasmic fragments from the bone marrow megarkaryocytes in mammals

38

what is the life span of platelets

10 days

39

when things end in ____osis what does that mean

an increase in agranocytes

40

when things end in ___penia what does that mean

a lower number than normal

41

when things end in ____ philia what does that mean

increase in granulocytes than normal

42

where is basophils produced

in the bone marrow

43

what are macrophages

-derived from blood monocytes
- can divide and are phagocytes

44

when you have an increase number of eosinophils what does that mean

hypersensitivity reactions or allergies and certain forms of parasitism

45

what is important about eosinophils in sight hounds

they can have slightly segmented nuclei, gray cytoplasm and vacuoles and granules cannot be seen (they don't stain)

46

what is the location of lymphocutes

lymph nodes, spleen, thymus, tonsils, GI lymphoid tissue, bronchial lymphoid tissue, bone marrow and blood

47

how small can lymphocytes be

7 to 9 microns

48

what is a medium size of lymphocytes

9 to 11 microns