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Flashcards in Lecture 1 Deck (29):
1

Janssen 1590-1608

First compound microscope

Two lens system

2

1655 Robert Hooke

Applied term cell to life's smallest units

3

Van Leeuwenhoek 1676

Simple microscope -single lens


Saw Protozoa and bacteria for the first time

4

When was cowpox vaccine against smallpox first tested ?

England 1700's

5

Edward Jenner

Cowpox against smallpox

6

Who and when proposed cell theory?

Schwann ,Schleiden
1800s

7

Who introduced antiseptics to prevent the disease?

Semmelweis ,hospital in Vienna

8

Who studied epidemic of cholera and where ?

London, 1800s , snow

9

What is Pasteur famous for ?

-showed that lactic acid fermentation was due to microbe

-shows that do not arise via spontaneous generation

10

Explain theory of Spontaneous Generation of Microorganisms?

Answer

11

What is Lister famous for ?

Antiseptic surgery and use of carbolic acid to maintain asepsis

12

Who discovers nucleic acid?

Miescher

13

What is R Koch known for?

-demonstrated that anthrax is caused by Bacillus anthracite

Uses gelatin to cultures bacteria

In his lab his assistants wife shows agar

Discovers tubercle bacillus

Gram stain development

14

What is Pasteur known for?

Rabies vaccine

15

Explain Kochs postulate...

Aaaaa

16

Who recognized archaea for the first time?

Woese and fox

17

What is virulence trait?

Virulence traits enable an organism to colonize a host and/or cause a disease

18

What it means to be Dimorphic Fungus?

Can sometimes grow as a yeast form and other times as a mold form •Several pathogenic fungi are dimorphic, growing as a mold form in the environment but as a yeast form when infecting an animal

19

Eukaryotic cell structure components?

Nucleus
SER. RER
Golgi
Peroxisomes
Lysosomes
Mitochondria
Flagella and cilla

20

What is the vesicular transport involved in uptake of large molecules in eukaryotic cells?

Endocytosis and phagocytosis

21

What is the function of Lysosomes?

Breakdown of macromolecules
They contain internal acid ph and acid hydrolyses

22

Where does the Glycolysis and Pentose Pathway occur?

Cytoplasmic matrix -custom

23

Where does the TCA cycle occur ?

Mitochondrial matrix

24

Size of eukaryotic ribosomes?

80s when translating an mRNA

Formed of 40s and 60s subunits

40s subunits contain rRNA 18s

25

How is destination of newly made protein determined?

By the location of ribosomes

26

How does flagella and cilia move?

Undulating motion due to complex microtubules core and cilary ATPase named ciliary dynein provides energy

27

Protozoan and animal cells lack cell walls

True /False

True

28

Fungal , algal and plant cells have cell walls

True/False

True

29

How does the transport across the plasma membrane occurs in eukaryotic cells?

Via ;simple diffusion, facilitated transport , active transport , iron channels or vesicular uptake during endocytosis