Lecture 1: Introduction to Pharmacology Flashcards Preview

PHAR 1602 McKechnie Pharmacology > Lecture 1: Introduction to Pharmacology > Flashcards

Flashcards in Lecture 1: Introduction to Pharmacology Deck (15)
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1
Q

Define the term pharmacology

A

The science of drug action on the function of biological systems

2
Q

What are drugs?

A

Any substance that produces a biological effect except nutrients

3
Q

Define the term pharmacokinetics

A

the study of absorption, distribution, metabolism and excretion of drugs

4
Q

Define the term pharmcodynamics

A

the study of molecular, biochemical and physiological effects of drugs on cellular systems and their mechanisms of action

5
Q

Where do drugs come from? Name examples

A

Animals: insulin, growth hormone, clotting factors
Plants: morphine, salicylic acid
Bacteria: Tacrolimus
Synthetic drugs made via chemical synthesis: acetylsalicylic acid (aspirin)

6
Q

Name an application of pharmacology

A

Treatment of diease

7
Q

Define psychotropic drugs and name examples of some with addictive potential

A

mind-altering

tobacco, alcohol, cocaine etc.

8
Q

Name the 7 drug targets and of these what are the 4 most common (most common are starred)

A
cellular*
proteins*
receptors*
GPCR*
ion channels
enzymes
transport proteins
9
Q

What are the role of transporter proteins in cells?

A

takes chemical or nutrient from one side of the cell to another

10
Q

what does an agonist do?

A

switches on or activates

11
Q

what does antagonist do?

A

blocks or inhibits agonist

12
Q

What are agonists and antagonists?

A

ligands - molecules which bind and occupy receptor

13
Q

in what two ways can drugs act on receptors

A

agonist - activate receptor

antagonist - stop natural agonist from binding

14
Q

What is physiology? Give an example

A

NORMAL operation of bodily functions e.g. insulin decreases blood glucose

15
Q

What is pathology? Give an example

A

changes in physiology associated with disease e.g. high blood glucose caused by insulin defficency