Lecture 11 Flashcards Preview

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Flashcards in Lecture 11 Deck (14):
1

How many layers are in the cerebellar cortex? What are the layers?

3
Molecular - outer
Purkinje
Granule cell layer - inner

2

What are the 4 inhibitory cell types in the cerebellar cortex?

Purkinje
Basket
Stellate
Golgi

3

What are the 3 excitatory cell types in the cerebellar cortex?

Granule
Mossy
Climbing

4

Which cells send output to deep cerebellar nuclei?

Purkinje

5

Which cells form a cluster around Purkinje cells? What is notable about these cells?

Basket
Potent because they synapse directly on Purkinje cell bodies

6

Which cells make up parallel fibers?

Granular cells

7

Which cell type do deep cerebellar neurons feedback on?

Inferior olivary nucleus

8

Which fibers create simple/single spikes?

Parallel

9

Which fibers create complex spikes?

Climbing

10

At base, do purkinje cells stimulate or inhibit the firing of deep cerebellar nuclei?

Inhibit!

11

What are the 3 ways that you might see an increase in deep nuclei firing?

Inverter - less Purkinje firing to create inhibition
T-type rebound - activation of Ca2+ channels after a bout of inhibition
Synchrony code - signals from multiple Purkinje at one time will remove inhibition (about timing of signals)

12

What is a gain up stimulus? What is the result?

Head moves in opposite direction of target
Eyes move faster than head

13

What is a gain down stimulus? What is the result?

Head moves in the same direction as the target
Eyes move slower than head

14

What phenomenon occurs in response to motor learning in terms of cerebellar plasticity?

Long term depression plasticity
Due to transient increase in complex spikes