Lecture 11: Gametogenesis Flashcards

1
Q

sperm gametogenesis

A

spermatogonium–>primary oocyte–>meiosis–>secondary oocyte –> meiosis —> spermatid

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2
Q

oogenesis

A

primary oocyte
primary oocyte in follicle
primary oocyte in larger follicle
secondary oocyte in larger follicle + polar body

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3
Q

when are mature sperm dormant until

A

puberty

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4
Q

spermatids to mature sperm called

A

spermiogenesis

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5
Q

where are sperm stored

A

epididymis (come from seminiferous tubules)

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6
Q

what happens for sperm to mature

A

golgi becomes part of acrosome, centrioles go to tail, mitochondria line up around beginning of tail (called thd middle piece)

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7
Q

what does normal spermatogenesis require

A

the Y chromosome

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8
Q

oogonia

A

primordial female sex cells

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9
Q

when do oogonia proliferate

A

fetal life via mitosis

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10
Q

when are primary oocytes formed

A

before birth (from oogonia)

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11
Q

primary oocytes

A

surrounded by flattened follicular cells

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12
Q

primordial follicle

A

primary oocyte enclosed by follicular cells

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13
Q

primary follicle

A

during puberty, primary oocyte enlarges and follicular cells become columnar. get zona pellucide

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14
Q

where are primary oocytes before puberty arrested (primary follicle)

A

prophase stage of first meiotic division

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15
Q

whre is the ovulated ovum arrested

A

metaphase II unless it gets fertilized

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16
Q

what does 1st meiotic division give rise to in oogenesis

A

secondary oocyte and polar body

17
Q

gametogenesis timing in female vs male

A
  • embryogenesis and arrests until puberty (female)

- begins at puberty (male)

18
Q

result of oogenesis vs spermatogenesis

A

one germ cell is one ovum and 2 polar bodies (female)

one germ cell is 4 mature spermatozoa (men

19
Q

GRH

A

released by neurosecretory cells in hypothalamus

20
Q

FSH

A

stim follicles, stim production of estrogen by follicular cells

21
Q

LH

A

triggers ovulation of secondary oocyte, stimulates follicular cells and corpus luteum

22
Q

what does corpus luteum secrete

A

progesterone and estrogen

23
Q

when does the follicle start pressing on the surface

A

tertiary stage

24
Q

corpus luteum arises from

A

walls of ovarian follicles which develop into gland structure

25
the primary follicle contains the
zona pellucida
26
what happens when ovulation occurs
secondary oocyte expelled (surrounded by zona pellucida and corona radiata), resumption of 1st meitoic division
27
3 phases of menstrual cycle
menstrual, proliferative, and luteal phase
28
proliferative phase
growth of ovarian follicles, controlled by estrogen, endometrium thickens
29
luteal phase
formation, functioning, and growth of corpus luteum. Progestterone stim glandular epithelium (glycogen rich!)
30
how is sperm transported
from epididymis to urethra through peristalsis of vans deference
31
where does fertilization normally occur
ampullary portion of fallopian tube
32
capacitation (pre fertilization)
glycoprotein coat and seminal proteins leave acrosome membrane cholesterol/phospholipid ratios altered increase in motility *takes place in uterus or tube and allows acrosome rxn to occur
33
changes during fertiliztion to sperm
acrosome rxn (acrosome binds to glycoprotein ZP3 on zona pellucida) fenestrations upon contact w corona radiata apertures btwn sperm plasma membrane and acrosome
34
what gets released during acrosome reaction
hyaluronidase and acrosin
35
phases of fertilization
penetration of corona radiata penetration of zona pellucida fusion of PM zona reaction (no more sperm!)
36
what happens if fertilization occurs
1) meiosis 2 of oocyte 2) female/male pronuclei form and then fuse ZYGOTE CREAATED!