Lecture 12 - enzymes II

Question 1

In Lineweaver-Burke, slope is equal to ________

Answer 1

Km/Vmax

Question 2

In Lineweaver-Burke, x-intercept is equal to _______.

Answer 2

-1/Km

Question 3

Bi substrate reactions require ______ of substrates

Answer 3

Sequential

Question 4

Inhibitor binding to the enzymes active site are a hallmark of ______ inhibition

Answer 4

Competitive

Question 5

Inhibitors that bind to an allosteric site are hallmarks of a(n) ________ inhibition

Answer 5

Uncompetitive

Question 6

Inhibitors that bind with either the enzyme or the ES complex is a hallmark of ______ inhibition.

Answer 6

Non-competitive

Question 7

On Lineweaver-Burke, y-intercept is _______

Answer 7

1/Vmax

Question 8

Changes to pH often change enzyme function by ______

Answer 8

Altering the 3-D shape of the protein, rendering it non-functional