Lecture 12 - Oral Manifestations of Dermatologic Diseases Flashcards Preview

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Flashcards in Lecture 12 - Oral Manifestations of Dermatologic Diseases Deck (14)
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1

Lichenoid

Idiopathic Lichen Planus
Lichenoid drug eruption
Lupus Erythematous
Graft v. Host Disease
Hepatitis C

2

Autoimmune Disease

Pemphigus vulgaris
Paraneoplastic pemphigus
Mucous membrane pemphigoid

3

Immune-Mediated

Erythema multiforme
Stevens-Johnson Syndrome
Toxic Epidermal Necrolysis

4

Idiopathic Lichen Planus

Reticular
-common
-lacy, white striations

Erythematous or Ulcerative
-less common
-desquamative gingivitis

Drug Rxn, Tx w/ topical corticosteroids

5

Desquamative Gingivitis

Peeling away of gingiva
Manifestation of lichen planus, hypersensitivity rxn, or pemphigoid
Sensitive to spicy food

6

Systemic Lupus Erythematous

Female, 30s

Lichenoid lesions of palate, buccal mucosa, or gingiva
Ulceration, pain, erythema, hyperkeratosis

Renal Failure

7

Chronic Cutaneous Lupus

Few systemic symptoms

Oral lesions
Lichen planus, fine white striae
Sensitive to acidic or salty foods

8

Graft v. Host Disease

Oral lesions in 33-75% of acute and 80% of chronic cases

White striae
Diffuse white papules on tongue, buccal, labial mucosa
Ulcers
Xerostomia

9

Pemphigus Vulgaris

Fatal
50yo

Antibody to desmosomes
Bullae
Intraepithelial separation above basal level

10

Paraneoplastic Pemphigus

Underlying neoplasm (CLL, Lymphoma, Thyoma)

Skin and oral bullae
Lip crusties
Eye scarring

11

Mucous Membrane Pemphigoid

Female, 50-60yo

Antibodies to hemidesmosomes
Ocular lesions
Intraepithelial separation below basal level

12

Erythema Multiforme

Secondary to infection (HSV or mycoplasma pneumoniae)

Male, 20-40yo

Hemorrhagic lip crusties, shallow ulceration
Perimeter of tongue
gingiva and hard palate spared

13

Stevens Johnson Syndrome

Drug rxn
head and trunk
oral, genital, and ocular lesions

14

Toxic Epidermal Necrolysis

>30% surface area involvement
Diffuse sloughing of skin & mucosal surfaces
Dehydration & infection
35% mortality rate