Flashcards in Lecture 2 - Blood transfusion Deck (16):
Who shouldn't you give platelet transfusion?
Immune thrombocytopenia purpura
Thrombotic thrombocytopenia purpora
Heparin induced thrombocytopenia + thrombosis
What is cryoprecipitate?
Factors 8 + 13
What is prothrombin complex concentrate?
What is it used for?
Concentrated vitamin K factors
Used to reverse warfarin
Define transfusion threshold?
The conc of Hb (or lower) in which a RBC transfusion is needed
What is fresh frozen plasma?
Contains all clotting factors needed.
Used to treat bleeding in patients with abnormal clotting results
To correct abnormal clotting prior to invasive procedures
What are the main symptoms of a transfusion reaction?
How to test for protein groups on RBC?
What is an acute transfusion reaction caused by incompatibility?
IgG reaction to RBC.
Back pain + chest pain
Fever + chills
What are the signs and symptoms of bacterial contaminated transfusion/
What are the signs + symptoms of febrile non-haemolytic transfusion
Mildly raised temp
What are the signs and symptom of an allergic reaction?
What causes it?
Occurs after transfusion of components that contains plasma
What are the signs and symptoms of an anaphylactic reaction?
What are the pulmonary complications of transfusion?
TACO - transfusion associated circulatory overload
TRALI - transfusion related acute lung injury
TAD - Transfusion associated dyspnoea
What are the symptom of TACO?
Acute left ventricular failure
What are the signs of TACO?
Elevated jugular venous pulse