Lecture 23 Flashcards

1
Q

What is glucose?

A

A hexose simple sugar monosaccharide

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2
Q

What is a hexose?

A

6 Carbon ring

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3
Q

What is the chemical structure of glucose?

A

C6H12O6

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4
Q

What is a carbohydrate?

A

A large macromolecule / polysaccharide

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5
Q

What are sources of glucose from carbohydrates?

A

Starch from plants and glycogen from meat

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6
Q

What is starch?

A

A polymer made up of up to 1 million glucose units joined by glycosidic bonds

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7
Q

What are the two forms of starch?

A

Amylose and amylopectin

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8
Q

What is the structure of amylose?

A

A liner polymer of glucose units

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9
Q

What is the structure of amylopectin?

A

A branched polymer of glucose units

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10
Q

What is glycogen?

A

A branched polymer of glucose units

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11
Q

What is a disaccharide?

A

two sugars joined by a glycosidic bond

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12
Q

What are the examples of disaccharides?

A

Sucrose, lactose and maltose

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13
Q

What is the structure of sucrose?

A

A glucose bound to a fructose by a glycosidic bond

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14
Q

Where are disaccharides found in the diet?

A

Fruit and raw sugar

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15
Q

What enzyme cleaves glycosidic bonds from polysaccharides to disaccharides?

A

Amylase hydrolase

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16
Q

What enzymes cleave the glycosidic bonds from disaccharides to monosaccharides?

A

Specific enzymes e.g. sucrase for sucrose

17
Q

What is the end result of digestion of carbohydrates?

A

Glucose in the GI tract

18
Q

Are sugars polar or non polar?

A

Highly polar

19
Q

Are sugars water or lipid soluble?

A

Water soluble

20
Q

How do glucose molecules cross the lipid membrane?

A

Through specific transporter proteins anchored in the membrane

21
Q

What are the two types of transpot?

A

Active and facilitated transport

22
Q

What is active transport?

A

The movement molecules against a concentration gradient, requiring energy input

23
Q

What transporter protein transports glucose via active transport across the membrane in the GI tract?

A

The sodium-glucose linked transporter

24
Q

What is facilitated transport?

A

The movement of molecules down a concentration gradient, not requiring energy input

25
What transporter protein transports glucose via facilitated transport across the membrane in the GI tract?
GLUT2
26
How is glucose used as a fuel molecule?
It is oxidised in glycolysis (in all organisms) which usually occurs in the cytoplasm in eukaryotes
27
Why is glucose essential as fuel for red blood cells?
RBCS do not have mitochondria and can therefore not utilise other pathways
28
What is the energy requirement in the brain?
120g of glucose per day
29
Do brain cells have mitochondria?
Yes
30
What is the traditional view on why the brain favours glucose?
Glucose easily crosses the blood-brain barrier and fats do not
31
What is the modern hypothesis as to why the brain prefers glucose?
It is safer, providing a quicker source of ATP without the risk of damage
32
Why is glucose favoured as a energy molecule in the eye cells?
High amounts of blood vessels and mitochondria would refract the light, so these are limited and glucose does not require either
33
Which muscle cells use fats as fuel?
Red muscle cells, for endurance
34
Which muscle cells use glucose as fuel?
White muscle cells, for sprinting