Lecture 24: Synaptic Networks Flashcards Preview

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Flashcards in Lecture 24: Synaptic Networks Deck (17):
1

Different types of neurotransmitters:

- Acetylcholine (ACh)
- Glutamate (EPSP)
- GABA (IPSP)
- Norepinephrine / Noradrenaline
- Dopamine
- Serotonin

2

Methamphetamine increases levels of....
It also blocks .... It lingers in the synaptic cleft. Also acting in the ____ _____, making it highly addictive.

- Noradrenaline
- Dopamine
- Serotonin
- Reuptake
- Reward centres

3

Almost all drugs target endogenous (______) systems.

- Receptor

4

Excitatory causes ______

- Depolarisation

5

Acetylcholine activatea stimulus-gated _____ channeles

- Na+

6

Inhibitory causes ______

- Hyperpolarisation

7

GABA activates _____ and ______ channels. This causes hyperpolarisation. (IPSP)

- Cl-
- K+

8

Can one cell have excitatory and inhibitory synapses?

- YES

9

EPSP =
IPSP =

- BLEEP (RMP)
- BLOOP (RMP)

10

Local Synaptic Potentials (EPSPS + IPSPS) summate at the ___ ___, and an action potential is either generated or not.

- Axon hillock

11

EPSP + EPSP =

- Big EPSP (larger depolarisation)
- AP generation all depends on threshold being reached or not

12

EPSP + IPSP =

- Nothing (they eliminate each other)
- AP generation all depends on threshold being reached or not

13

What is spatial summation?

- We receive different signals at different sides of a neuron, at the axon hillock, both signals are summated
- Signals come from DIFFERENT places
- AP is generated if neuron is above threshold

14

What is temporal summation?

- Signals arriving at the same synaptic knob within a short time range of each other integrate
- Takes more time for repolarisation of local potentials if an AP is generated

15

What happens if excitatory and inhibitory signals arrive at the same time?

- AP generation all depends on threshold being reached or not

16

Describe the divergence network:

- Something where one signal from one neuron is being transmitted to more than one neuron
- A single neuron DIVERGES to multiple neurons
- Opportunity to amplify signals
- Few control points

17

Describe the convergence network:

- Multiple neurons CONVERGE to a single neuron that initiates a single response
- If you're preparing dinner and you cut yourself you can either know you've cut yourself by seeing that you've cut yourself or the pain receptors let you know
- Back-up route, multiple neurons converge to a single neuron to move away hand that's holding knife :D