Lecture 25 - Glycolysis & Gluconeogenesis Flashcards Preview

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Flashcards in Lecture 25 - Glycolysis & Gluconeogenesis Deck (13)
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1
Q
The reaction of glucose to \_\_\_\_\_\_\_ is governed by hexokinase.
Hexokinase is inhibited by \_\_\_\_\_\_\_\_\_\_\_\_.
A. G-6-P; G-6-P
B. G-6-P, F-1,6-BP
C. G-1-P, F-2,6-BP
C. F-1-P, ATP
A

A. G-6-P, G-6-P

2
Q
G-6-P to \_\_\_\_\_ is governed by phosphofructokinase. 
PFK is inhibited by \_\_\_\_\_\_\_ and \_\_\_\_\_.
A. F-1,6-BP, G-6-P
B. ATP, Citrate
C. AMP, F-2,6-BP
D. F-1,6-BP, AMP and F-2,6,BP
A

B. ATP, Citrate

3
Q
Pyruvate kinase catalyzes the reaction of PEP to \_\_\_\_\_. This reaction is inhibited by \_\_\_\_\_\_.
A. DHAP; F-2,6-BP and ATP
B. 3-PG; F-1,6-BP & Insulin
C. Pyruvate; Alanine, ATP, and Glucagon
D. Pyruvate; Insulin and F-1,6-BP
A

C. Pyruvate; Alanine, ATP, and Glucagon

4
Q
G-6-P to \_\_\_\_\_ is governed by phosphofructokinase. 
PFK is stimulated by \_\_\_\_\_\_\_ and \_\_\_\_\_.
A. F-1,6-BP, G-6-P
B. ATP, Citrate
C. AMP, F-2,6-BP
D. F-1,6-BP, AMP and F-2,6,BP
A

D. F-1,6-BP, AMP and F-2,6,BP

5
Q
Pyruvate kinase catalyzes PEP to pyruvate. This reaction is stimulated by:
A. F-2,6-BP and ATP
B. F-1,6-BP and Insulin
C. F-2,6-BP and insulin
D. F-1,6-BP
A

D. F-1,6-BP

6
Q
Insulin transporter in the brain; high glucose affinity
A. GLUT 1
B. GLUT 2
C. GLUT 3
D. GLUT 4
A

A. GLUT 1

7
Q

Main GLUT in neurons

A. GLUT 1
B. GLUT 2
C. GLUT 3
D. GLUT 4

A

C. GLUT 3

8
Q

Insulin dependent GLUT in skeletal m., heart, adipose.

A. GLUT 1
B. GLUT 2
C. GLUT 3
D. GLUT 4

A

D. GLUT 4

9
Q

Main GLUT in liver, low affinity without regulation.

A. GLUT 1
B. GLUT 2
C. GLUT 3
D. GLUT 4

A

B. GLUT 2

10
Q

Fructose can enter glycolysis at what location(s)?

A. G-6-P and F-1-P
B. DHAP and GAP
C. G-6-P and F-6-P

A

B. DHAP and GAP

11
Q

Translocation of this enzyme into the nucleus of hepatocytes helps stop glycolysis in the presence of low blood sugar.

A

Glucokinase (low insulin=low blood sugar=high glucagon)

12
Q

This is the rate limiting step of glycogen production

A

Glycogen synthase activity (addition of glucose to chain)

13
Q

Rate limiting step in glycogen breakdown

A

Glycogen phosphorylase activity (cleavage of glycogen)