Lecture 25 - Glycolysis & Gluconeogenesis Flashcards Preview

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Flashcards in Lecture 25 - Glycolysis & Gluconeogenesis Deck (13):
1

The reaction of glucose to _______ is governed by hexokinase.
Hexokinase is inhibited by ____________.
A. G-6-P; G-6-P
B. G-6-P, F-1,6-BP
C. G-1-P, F-2,6-BP
C. F-1-P, ATP

A. G-6-P, G-6-P

2

G-6-P to _____ is governed by phosphofructokinase.
PFK is inhibited by _______ and _____.
A. F-1,6-BP, G-6-P
B. ATP, Citrate
C. AMP, F-2,6-BP
D. F-1,6-BP, AMP and F-2,6,BP

B. ATP, Citrate

3

Pyruvate kinase catalyzes the reaction of PEP to _____. This reaction is inhibited by ______.
A. DHAP; F-2,6-BP and ATP
B. 3-PG; F-1,6-BP & Insulin
C. Pyruvate; Alanine, ATP, and Glucagon
D. Pyruvate; Insulin and F-1,6-BP

C. Pyruvate; Alanine, ATP, and Glucagon

4

G-6-P to _____ is governed by phosphofructokinase.
PFK is stimulated by _______ and _____.
A. F-1,6-BP, G-6-P
B. ATP, Citrate
C. AMP, F-2,6-BP
D. F-1,6-BP, AMP and F-2,6,BP

D. F-1,6-BP, AMP and F-2,6,BP

5

Pyruvate kinase catalyzes PEP to pyruvate. This reaction is stimulated by:
A. F-2,6-BP and ATP
B. F-1,6-BP and Insulin
C. F-2,6-BP and insulin
D. F-1,6-BP

D. F-1,6-BP

6

Insulin transporter in the brain; high glucose affinity
A. GLUT 1
B. GLUT 2
C. GLUT 3
D. GLUT 4

A. GLUT 1

7

Main GLUT in neurons

A. GLUT 1
B. GLUT 2
C. GLUT 3
D. GLUT 4

C. GLUT 3

8

Insulin dependent GLUT in skeletal m., heart, adipose.

A. GLUT 1
B. GLUT 2
C. GLUT 3
D. GLUT 4

D. GLUT 4

9

Main GLUT in liver, low affinity without regulation.

A. GLUT 1
B. GLUT 2
C. GLUT 3
D. GLUT 4

B. GLUT 2

10

Fructose can enter glycolysis at what location(s)?

A. G-6-P and F-1-P
B. DHAP and GAP
C. G-6-P and F-6-P

B. DHAP and GAP

11

Translocation of this enzyme into the nucleus of hepatocytes helps stop glycolysis in the presence of low blood sugar.

Glucokinase (low insulin=low blood sugar=high glucagon)

12

This is the rate limiting step of glycogen production

Glycogen synthase activity (addition of glucose to chain)

13

Rate limiting step in glycogen breakdown

Glycogen phosphorylase activity (cleavage of glycogen)