Flashcards in Lecture 3 Resp Failure (FYI missed this lecture) Deck (19):
Normal PO2 is ___
Normal CO2 is ____
Normal HCO3 is ____
normal pH is ____
Respiratory failure is due to either a _____ failure or a _____ failure
Gas exchange failure is manifested by _____; ventilatory failure is manifested by _____ and can be due to 3 reasons
hypercapnic (aka hypercarbic)-CNS depression, mechanical defect, fatigue
hypoxemic respiratory failure is characterized by ____ less than 60 mm Hg. hypercapnic failure is characterized by ____ > 45 mm Hg and a pH less than ____
increased deadspace causes what kind of RF? what about a V/Q mismatch?
with hypoxic/hypoxemic RF, what happens to PaCO2?
what happens to Pa O2 in ventilatory failure?
no change or decreases;
decreases (not as much as hypoxemic)
When V/Q = 0, there is a ____ obstruction. This is also called a ____. Does 100% O2 help?
When V/Q = infinity, there is ____ obstruction. This is also called ____. Does 100% O2 help?
physiologic dead space;
with diffusion abnormalities, there is an increased distance between ___. the alveolar capillary membrane is _____
hypoventilation causes a buildup of ____ in the lung, causing ____ respiratory failure
acute respiratory failure causes a large drop in ____.. Chornic RF causes a decrease in ____ slightly, but increases _____
example of cause of acute RF;
what about chronic RF?
2 neuromuscular causes of hypercapnic RF:
MS, muscular dystrophy
(Also probably myasthenia gravis)
Clinical manifestations of resp failure:
severe ____ headache; late sign is ____; early sign is tachycardia, ____, and mild HTN
hypoxemia and hypoxia causes metabolic ____. there is a ____ in cardiac output and _____ renal function
RF clinical manifestations:
____, ____ breathing pattern; sitting ____, and dyspnea. There is also ____ breathing and retractions
problems of oxygen toxicity:
suppression of _____, leading to increased ___ and narcosis. absorption ____ and premature retrolental ____
Resorption atelectasis (collapse) is due due depletion of blood ____