Lecture 39 - Learning and Memory - AMPA-R Flashcards

1
Q

Explicit memory of facts, events, people, etc. Located in the temporal lobe.

A. Declarative
B. Procedural

A

A. Declarative

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2
Q

Sustained action potentials that remain long after NT release

A

Long Term Potentiation

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3
Q

Memory for perception and mental operations.

A. Declarative
B. Procedural

A

B. Procedural

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4
Q

Long term potentiation is induced by the NT _____ in the hippocampus.

A. Asparagine
B. Nitric oxide
C. Glutamate
D. Tyrosine

A

C. Glutamate

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5
Q

Low frequency stimulation of the NMDA receptor produces small amounts of Ca2+ influx. This acts to _____ Inhibitor-1 through ______.

A. activate; maintaining phosphorylation
B. activate; maintaining dephosphorylation
C. deactivate; maintaining phosphorylation
D. deactivate; maintaining dephosphorylation

A

B. activate; maintaining dephosphorylation

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6
Q

This receptor is translocated to the membrane with high amounts of Ca2+ influx.

A

AMPA

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7
Q

Large amounts of Ca2+ that influx through the NMDA receptor activate _____.

a. Calcineurin
b. Inhibitor-1
C. Adenylate cyclase

A

C. adenylate cyclase

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8
Q

Adenylate cyclase produces large amounts of _____, which directly activates _____.

a. cAMP; Inhibitor-1
b. cAMP; PKA
c. CamK; Inhibitor-1
d. Calcineurin; PKA

A

b. cAMP; PKA

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9
Q

PKA is responsible for the dephosphorylation of _____.

A

PP-1

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10
Q

Autophosphorylation of ____ produces translocation of the AMPA receptor to the PM.

A

CamK

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11
Q

Draw the low frequency path of synaptic plasticity.

A

Check drawing

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12
Q

Draw the high frequency path of synaptic plasticity.

A

check drawing

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13
Q

During surgeries in epileptic patients, the _____ was stimulated, evoking memories thought repressed.

A. Cortex
B. Medulla
C. Hippocampus
D. Pontine nucleus

A

C. hippocampus

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