Lecture 39 - Learning and Memory - AMPA-R Flashcards Preview

Biochemistry > Lecture 39 - Learning and Memory - AMPA-R > Flashcards

Flashcards in Lecture 39 - Learning and Memory - AMPA-R Deck (13):
1

Explicit memory of facts, events, people, etc. Located in the temporal lobe.

A. Declarative
B. Procedural

A. Declarative

2

Sustained action potentials that remain long after NT release

Long Term Potentiation

3

Memory for perception and mental operations.


A. Declarative
B. Procedural

B. Procedural

4

Long term potentiation is induced by the NT _____ in the hippocampus.

A. Asparagine
B. Nitric oxide
C. Glutamate
D. Tyrosine

C. Glutamate

5

Low frequency stimulation of the NMDA receptor produces small amounts of Ca2+ influx. This acts to _____ Inhibitor-1 through ______.

A. activate; maintaining phosphorylation
B. activate; maintaining dephosphorylation
C. deactivate; maintaining phosphorylation
D. deactivate; maintaining dephosphorylation

B. activate; maintaining dephosphorylation

6

This receptor is translocated to the membrane with high amounts of Ca2+ influx.

AMPA

7

Large amounts of Ca2+ that influx through the NMDA receptor activate _____.

a. Calcineurin
b. Inhibitor-1
C. Adenylate cyclase

C. adenylate cyclase

8

Adenylate cyclase produces large amounts of _____, which directly activates _____.

a. cAMP; Inhibitor-1
b. cAMP; PKA
c. CamK; Inhibitor-1
d. Calcineurin; PKA

b. cAMP; PKA

9

PKA is responsible for the dephosphorylation of _____.

PP-1

10

Autophosphorylation of ____ produces translocation of the AMPA receptor to the PM.

CamK

11

Draw the low frequency path of synaptic plasticity.

Check drawing

12

Draw the high frequency path of synaptic plasticity.

check drawing

13

During surgeries in epileptic patients, the _____ was stimulated, evoking memories thought repressed.

A. Cortex
B. Medulla
C. Hippocampus
D. Pontine nucleus

C. hippocampus