Lecture 4&6: Lymphoid Tissue I & II Flashcards Preview

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Flashcards in Lecture 4&6: Lymphoid Tissue I & II Deck (100):
1

What is the arrow pointing at and where would you find this tissue?

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Arrow is pointing at CT and this is GI tissue

2

What is the arrow pointing at and where would you find this tissue?

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The airway is pointing at CT and this is airway tissue 

3

What is this a picture of?

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Primary nodule (singular nodular tissue - non-encapsulated lymphoid tissue)

- Far more infrequent than secondary nodules 

- Consist of only small lymphocytes 

- Prenatal

- do not possess a germinal center 

4

What is the circle and the 2 arrows in this picture?

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Circle = secondary lymphoid nodule (singular nodular tissue, non-encapsulated lymphoid tissue)

Left arrow = mantle zone 

Right arrow = germinal center 

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5

What is this a picture of?

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Secondary lymph nodule 

6

What is this a picture of?

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Primary lymph nodule 

7

Name the 3 tonsils in the picture 

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Top = pharyngeal tonsil (adenoids)

Middle = palatine tonsils 

Bottom = lingual tonsils 

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8

What type of tonsil is this and what are the 2 arrows indicating?

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Pharyngeal tonsil 

Top arrow = pseudostratified columnar ciliated epithelium 

Bottom arrow = germinal center 

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9

What type of tonsil is this and what are the arrows indicating?

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Palatine tonsil 

Top arrow = stratified squamous epithelium 

next = partial capsule

Next = germinal centers

Bottom = crypts

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10

What is this a picture of and what do the arrows indicate?

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Lingual tonsil 

Top arrow = stratified squamous epithelium 

Bottom arrow = one crypt per tonsil 

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11

What is this a picture of?

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Palantine tonsil 

12

What is this a picture of?

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Lingual tonsil 

13

What is this a picture of?

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Pharyngeal tonsil 

14

What do the arrows in this picture indicate?

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Left = ileum

Middle = villi 

Right = lymphoid tissue 

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15

What does the box in this picture indicate?

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GALT -> AKA Peyers patches 

16

Where is this tissue found?

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Small intestine 

17

Where is this tissue found?

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Vermiform appendix

18

Where is MALT found?

GI tract, respiratory passageways and urinary tract 

19

GALT is called Peyers patches in the ileum and is characterized by an abundance of ______

Villi

20

GALT in the vermiform appendix is characterized by crypts and no ______

villi

21

How many palatine tonsils does a person have 

2

22

How many pharyngeal tonsils does a person have 

1

23

How many lingual tonsils does a person have?

Small and numerous 

24

Where are palatine tonsils found?

Lateral walls of oral cavity 

25

Where are pharyngeal tonsils found?

Posterior of nasopharynx 

26

Where are lingual tonsils found?

Posterior third of tongue

27

How many crypts are found in palatine tonsils?

Many! 10-20

28

How many crypts are found in pharyngeal tonsils?

None 

29

How many crypts are found in lingual tonsils?

1

30

What type of epithelium are palatine tonsils?

non-keratinized stratified squamous

31

What type of epithelium is found in pharyngeal tonsils?

Ciliated pseudustratified columnar 

32

What type of epithelium is found in lingual tonsils?

Stratified squamous 

33

Which lingual tonsil has a thick capsule?

Palantine tonsil 

34

What tonsil has a thin capsule?

Pharyngeal tonsil 

35

What tonsil has no difinitive capsule?

Lingual 

36

What is this an image of?

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The thymus pre-puberty 

37

What is this an image of?

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The thymus post-puberty

38

Label the arrows in the picture 

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Top arrow = cortex 

Next = medulla 

Next = capsule 

Bottom arrow = septum 

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39

Label the arrows in the image 

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Top = cortex 

Bottom = Septum 

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40

What structure is in this picture and where, in what organ is it found?

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Hassels corpuscles found in the thymus -> ONLY in the medulla 

41

What type of tissue is this and where is it found?

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Capsulated lymphoid tissue in the thymus 

42

Label the arrows in this picture 

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Top = capsule 

Next = cortex 

Next = medulla 

Last = Hassals corpuscle 

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43

What organ is this?

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Spleen -> no lobules 

44

Where is this tissue found?

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Spleen

45

Label A-D of the splenic tissue 

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A) Capsule

B) Trabecula 

C) Red pulp 

D) White pulp 

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46

Label 1-5

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1) germinal center 

2) corona 

3) marginal zone 

4) periarteriolar lymphoid sheath 

5) central arteriole 

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47

Label the arrows of the splenic tissue 

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Both are marginal zones 

48

Label the arrows of the splenic tissue 

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Top = splenic cord 

Bottom = splenic sinusoid 

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49

Label the arrows of the splenic tissue 

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Top = splenic cord 

bottom = splenic sinusoid 

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50

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51

Label A-E

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A) Germinal center 

B) Mantle 

C) Lymphatic nodule 

D) Inner cortex 

E) Outer cortex 

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52

Where would you find this tissue?

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Lymph node

53

Label the arrows and state where you would find this tissue 

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Top = medullary sinus 

Bottom = medullary cord 

This tissue is found in the lymph nodes 

54

Label A-C

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A) Capsule

B) Cortex 

C) Medulla 

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55

Label D-F

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D) Germinal center 

E) Mantle 

F) Lymphatic nodule 

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56

Label G-I 

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G) Medullary sinus 

H) Medullary cord 

I) Hilum 

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57

Where is this tissue found? Is there a capsule, lobules, cortex, or medulla?

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lymph node: capsule, cortex and medulla, but no lobules 

58

What is this structure?

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Lymph node 

59

What structures are seen here?

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Hassels corpuscles of the thymus 

60

What is this structure?

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The appendix 

61

What is this structure?

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A primary nodule 

62

What structures lymphoid structures are capsulated?

Thymus, spleen and lymph nodes 

63

Of the capsulated lymphoid organs, which are lobulated and which arent?

Lobules = thymus 

No lobules = spleen, lymph nodes 

64

What capsulated lymphoid organ decreases in size with age?

Thymus 

65

The thymus is the only capsulated lymphoid organ that is lobulated. How many lobules does it possess?

2

66

What structure does the medulla of the thymus contain?

Hassals corpscles 

67

Does the thymus contain germinal centers?

No!

68

What cell types does the cortex of the thymus contain?

Subscapular thymic epithelial cells 

Thymic cortical epithelial cells 

Maturing T cells (developing thymocytes)

69

What cell types are found in the medulla of the thymus?

Hassals corpuscles

Thymic medullary epithelial cells 

Dendritic cells 

70

Are macrophages present in the thymus?

Yes! Present in both the cortex and the medulla 

71

What is the site of mature lymphocytes in the thymus?

Medulla

72

How does the staining differ between the cortex and the medulla?

Cortex = darker 

Medulla = lighter 

73

What is the role of hassals corpuscles?

Release a factor that stimulates thymic DCs to complete maturation of T cells 

74

Where is the thymus-blood barrier found and what is its role?

Only exists in the cortex and prevents most circulating Ags from reaching developing T cells 

75

What is the role of macrophages in the spleen?

Destroy old RBCs

76

___________ extend from the capsule and divide the spleen into incomplete compartments

Trabeculae

77

Does the spleen contain a cortex or medulla?

No

78

What is the white pulp of the spleen rich in?

Lymphoid tissue 

79

What is the red pulp of the spleen rich in?

RBCs

80

What cell types are found in the corona of the spleen?

B cells and APCs 

81

What is the marginal zone of the spleen?

Where red and white pulp interact 

82

What cell type is found in the periarteriolar lymphoid sheath?

T cells 

83

The ________ arteries and the small capillaries of the spleen that they produce are sheathed by macrophages, that are responsible for removing damaged RBCs and particles from the blood 

penicillar 

84

Central arteries leave the white pulp and enter the red pulp as ___________ arteries, which either end in the splenic _________ (closed circulation) or into the ______________ (open circulation)

penicillar; sinusoids; red pulp

85

_________ arteries produce radial arteries while in the white pulp that feed into the marginal zone sinuses 

Central 

86

________ arteries divide into central arteries which penetrate the white pulp and are surrounded by periarteriolar lymphoid sheaths 

trabecular

87

_________ artery divides into trabecular arteries which follow the trabeculae into parenchyma of the spleen 

Splenic 

88

What are the smallest, most numerous encapsuated lymphoid organs?

lymph nodes 

89

What cell type is the outer cortex of LNs rich in?

B cells

90

What cell type is the inner cortex rich in?

T cells 

91

What cell types is the medullary cords of LNs primarily made up of?

Macrophages and plasma cells 

92

Where is the lymph cleared of 90% of Ags and cellular debris?

THe sinuses of the LNs

93

What are medullary sinuses?

Found in LNs -> spaces lined by endothelial cells surrounded by reticular cells and macrophages 

94

Out of the lymphoid organs: thymus, LNs, spleen, and tonsils, which have a cortex and medulla?

thymus and LNs

95

Out of the lymphoid organs: thymus, LNs, spleen, and tonsils, which have lymphoid nodules?

LNs, spleen, tonsils

96

Out of the lymphoid organs: thymus, LNs, spleen, and tonsils, which have cords and sinuses?

LNs and spleen 

97

WHat is the diagnostic feature of the thymus?

Hassalls corpuscles 

98

What is the diagnostic feature of the LNs

Cortical nodules and subcapsular sinus

99

What is the diagnostic feature of the spleen?

Central arteries 

100

What is the diagnostic feature of the tonsils 

epithelial covering