Lecture 4 - Epithelium and Glands Flashcards

1
Q

The Seven Functions of Epithelium

A
Protection
Absorption
Transcellular Transport
Selective Permeability
Surface Transport
Secretion
Sensation
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2
Q

Two Forms of Epithelia

A

In Epithelia As Sheets

In Glands Derived

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3
Q

Mesothelia

A

Membrane lining outer surface of cavity or organ

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4
Q

Serosa

A

Lines many regions of intestines CONSISTS OF MESOTHELIUM AND CONNECTIVE TISSUE

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5
Q

Endothelium

A

Lining internal surface of heart lymph, or blood vessels

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6
Q

Epithelium Always has

A

Basement Membrane

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7
Q

Characterisistics of Epithelium

A
Surface Sheet
Avascular
Decreased ECM
Dynamic
Polarized (oriented)
Cell Surface specialized
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8
Q

Free Vs Attached Epithelial

A

for a sheet the free is free on the lumen, and the attached is attached

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9
Q

Luminal and Abluminal Epithelial

A

Luminal is on the lumen and abluminal base

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10
Q

Apical, Lateral, and Basal, on a epithelial Cell

A

Apical is on the luminal side
Basal is on the basement membrane
Lateral is middle

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11
Q

Apical Surface Specializations (Name 3)

A

Microvilli, Cilia, Steriocilia

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12
Q

Microvilli

A

Increase SA, Function in Absorption, covered in glycolyx rich in Carbohydrates

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13
Q

How To Stain for Microvilli

A

PAS Stain (rich in carbohydrates)

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14
Q

Cilia

A

Longer than microvilli, help in moving substances across the surface

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15
Q

Steriocilia

A

Very long processes

only in male reproductive system and inner ear

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16
Q

Lateral junctional complexes (List the three)

A

Tight Junctions
Adhering Junctions
Gap Junctions

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17
Q

Tight Junctions

A

Seals Adjacent Cells

Keep transmembrane proteins from floating from the side they are on

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18
Q

Adhering Junctions (Two TypeS)

A

Generally mechanical stability and unity
Zonula Adherens - formed by transcellular proteins
Macula Adherens - formed by plaques and specialized filaments

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19
Q

Difference of Tight Junctions and Adherens

A

Tight Junctions cut the lumen away from the rest, and keep specializations in that area
Adherens hold things tight together

20
Q

Gap Junctions

A

Specialized Area Allows Cell Cell Communication, passage of small molecules

21
Q

Basement Membrane (two Parts)

A

Basal Lamina

lamina reticularis

22
Q

Basal Lamina (produced by and what collagen)

A

Made by Epithelia has type IV collagen

23
Q

Hemidesmosomes

A

Anchor the basal lamina to the epithelia

24
Q

Lamina Reticularis (produced by and what collagen)

A

Like the pad of the rug
manufactured by connective tissue
type III Collagen

25
Basal Infoldings
Infolding of the basal region of the cell Increases Surface Area Seen in places of transport Site of pumps and mitochondria visually looks like striations with mitochondria
26
The Two Basal Cell surface specializations
Basal Infoldings and Basement membrane
27
Pseudostratified Epithelium
Appears Stratified but is really one later, and they all attach to the basement membrane
28
Simple Squamus (two Examples)
Cells so flat, any thickness is nucleus bulging into the lumen ex// endothelium and mesothelium
29
Simple Cuboidal
Seen in ducts of glands for secretion and absorption
30
Simple Columnar
Used for absorption and Secretion Often with microvilli located in the GI
31
Stratified Squamous Non-keratinized
See nucleus in outer most layer | not hardened by karatin so maintains moist surface and protects underlying
32
Stratified Squamous Keratinized
Cytoplasm filled with keratin. Make rougher surface adds layer of protection no nuclei (shed) ex// Skin and tongue
33
Pseudostratified
Often ciliated found in respiratory system only columnar reach surface
34
Transitional Epithelium
Located Exclusive in urinary tract when relaxed its cuboidal, when stretched its squamous walls of bladder
35
Metaplasia
Reversible change of epithelia type to other
36
Dysplasia
Disordered growth leading to neoplasm
37
Neoplasia
New Growth of tissue and increase in number of cells
38
carcinoma
malignant tumor of epithlelium tissue
39
Adenocarcinoma
malignant tumor of glandular epithelial tissue
40
Gland Formation
Originally were epithelial tissue and then becomes gland through invagination. Can be unicellular or multicellular
41
Exocrine Gland
Maintains contact with epithelial and secrete through duct
42
Endocrine Gland
Ducltess secrete hormones usually distribute thorugh the blood removes contact with epithelial gets invaded by blood vessels
43
Exocrine and Endocrine where it secretes
Exocrine - secrete apically | Endocrine Secrete basally
44
Merocrine
Secretion from Exocrine via exocytosis
45
Apocrine
Small Portions of cytoplasm release with product
46
Holocrine
Secretory cell is destroyed, whole cell becomes part of product
47
Serous vs Mucous Secretion
Serous is watery and often enzymes | Mucous is viscous with glycoprotein content