Lecture 4: Introduction to Pharmacology and Scope Flashcards Preview

Neuro II Exam 1 - Pharm Week > Lecture 4: Introduction to Pharmacology and Scope > Flashcards

Flashcards in Lecture 4: Introduction to Pharmacology and Scope Deck (21):
1

The MOA of a drug and how the Drug affects the body is known as?

PharmacoDynamics

2

A drug which resides in an inactive form (as manufactured) and when administered is transformed (metabolized) into an active compound (capable of inducing pharmacological effect) is known as what?

Pro-drug

3

What 3 criteria are used for Pharmaceutical equivalence?

1) Same active ingredients

2) Same dosage form/route of administration

3) Same strength/concentration of active ingredient

*And meet the same standards for quality/purity

4

A field of study of the appropriate use of medications to effectively treat or prevent disease and manage symptoms, using evidence-based medicine, is known as?

Pharmacotherapeutics

5

What is the definition of Pharmaceutical alternatives?

i.e., what is the same and what is different

Same active drug but different salts/complexes, or different dosage forms or strengths

6

What is Bioequivalence and the % range?

- Similar rate and extent of absorption

- 80-125% of reference product

7

What is the criteria for a drug to be considered therapeutically equivalent?

i.e., what 2 types of equivalence and also must have the same what?

- Must be pharmaceutically-equivalent and bio-equivalent AND expected to have the same:

1) Therapeutic (clinical) effect

2) Safety profile

8

What are the 3 pregnancy risk categories for drugs used by the FDA?

1) Pregnancy (includes labor and delivery)

2) Lactation (includes nursing mothers)

3) Females and Males of Reproductive potential

9

What are the 2 categories of legend drugs (prescription required)?

1) Non-scheduled/Non-controlled: NO abuse potential

2) Scheduled/controlled (C-I thru C-V): based on abuse potential

10

How does the number designation C-I thru C-V related to the abuse potential of scheduled drugs?

Lower risk of abuse the higher the number (i.e., C-IV or C-V)

11

The numeric designation of scheduled drugs has an impact on what 3 things?

- Dispense quantitiy

- Refills allowed

- Prescriptions' life-span

12

What is q.h.s?

Every night at bedtime

13

What is a.c. vs. p.c.?

- a.c. = before meals

- p.c. = after meals

14

Differentiate o.d., o.s., and o.u. for administration of drugs for the eye.

o.d. = right eye

o.s. = left eye

o.u. = both eyes

15

Differentiate a.d., a.s., and a.u. for administration of drugs for the ears.

a.d. = right ear

a.s. = left ear

a.u. = both ears

16

What is gtt?

Drops

17

What is ut. dict. (u.d.)?

As directed

18

What is t.r.a.?

To run at

19

What is k.v.a.?

Infusion rate?

Keep vein open (a "slow" infusion rate)

20

What does D5W/D10W/D50W refer to?

- "x"% dextrose in water

- D5W = 5% dextrose in water = 5 grams in 100 mL

21

If you give 25cc of D50W how many grams of dextrose were given?

12.5 g 

*25cc = 25 mL and there are 50g of dextrose per 100 mL