Flashcards in Lecture5 Deck (8)
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1
Q
using SC or IM, is lipid or water soluble faster?
A
water soluble
2
Q
bioavailability is mathematically:
A
AUCoral/AUCiv=F
smaller F means it is likely means given IV and not PO
3
Q
distribution:
A
REVERSIBLE transfer of drug from general circulation to other parts of the body
4
Q
Vd (volume of distribution)-
A
Dose(t0)/Plasma drug concentration
5
Q
High plasma drug concentration means…
A
low Vd
6
Q
Low plasma drug concentration means…
A
high Vd
7
Q
over 40 Vd means
A
drug is in tissue
8
Q
order of drug distribution between tissue?
A
VRG/blood, muscle, tissue