Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

PHRM 825 - Exam 3 > LECTURES 27 & 28 - asthma > Flashcards

LECTURES 27 & 28 - asthma Flashcards

(55 cards)

Start Studying
1
Q

List factors that increase the risk for asthma exacerbation

A

SABA overuse
Inadequate ICS exposure
Concurrent medical conditions
Environmental exposures (air quality)
Low FEV1 (<60% predicted)
Higher blood eosinophils
>/= 1 severe exacerbations in the last year

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Define maintenance therapy / treatment

A

Asthma treatment that is prescribed for daily use - treatment is intended to be used daily regardless of symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Define “reliever” (treatment/therapy)

A

Treatment taken PRN for relief of symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Define MART (maintenance & reliever therapy)

A

Treatment of ICS/formoterol for daily use (maintenance tx) and for use in asthma symptom relief

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the goals of therapy for obtaining asthma control?

A

Asthma symptom control
Exacerbation risk reduction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

When initiating pharmacotherapy for asthma, what “step” would a patient be if they:
experience symptoms < 3-5 days/week
do NOT experience nighttime awakenings
have NOT had a recent exacerbation

A

step 1-2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

When initiating pharmacotherapy for asthma, what “step” would a patient be if they:
experience symptoms most days
experience nighttime awakenings once a week or more
have NOT had a recent exacerbation

A

step 3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

When initiating pharmacotherapy for asthma, what “step” would a patient be if they:
experience symptoms daily
experience nighttime awakenings once a week or more
have had a recent exacerbation

A

step 4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is an important patient counseling point for inhaled corticosteroids?

A

Rinse mouth out and spit after each use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

List common side effects of inhaled corticosteroids

A

dysphonia, oral candidiasis (thrush), cough, HA, hoarseness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the dosing of inhaled corticosteroids based on?

A

based on low, medium, and high intensity steroid dose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

List the brand names of inhaled corticosteroids (ICS)

A

Alvesco
Arnuity
Asmanex
Flovent
Pulmicort
QVAR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

List the generic names of inhaled corticosteroids (ICS)

A

ciclesonide
fluticasone furoate
mometasone furoate
fluticasone propionate
budesonide
beclomethasone dipropionate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

List the brand/generic names for ICSs

A

Alvesco (ciclesonide)
Arnuity (fluticasone furoate)
Asmanex (mometasone furoate)
Flovent (fluticasone propionate)
Pulmicort (budesonide)
QVAR (beclomethasone dipropionate)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is Alvesco (ciclesonide) available as?

A

HFA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is Arnuity (fluticasone furoate) available as?

A

Ellipta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is Asmanex (mometasone furoate) available as?

A

HFA, Twisthaler

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is Flovent (fluticasone propionate) available as?

A

HFA, Diskus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is Pulmicort (budesonide) available as?

A

Flexhaler

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is QVAR (beclomethasone dipropionate) available as?

A

Redihaler

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

List the brand/generic names of SABAs

A

albuterol
ProAir (albuterol)
Proventil (albuterol)
Ventolin (albuterol)
Xopenex (levalbuterol)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What is albuterol (generic) available as?

A

HFA, nebulizer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What is ProAir (albuterol) available as?

Study These Flashcards
A

HFA, RespiClick, Digihaler

24
Q

What is Proventil (albuterol) available as?

25
What is Ventolin (albuterol) available as?
HFA
26
What is Xopenex (levalbuterol) available as?
HFA, nebulizer
27
List the brand/generic of LABAs
Serevent (salmeterol)
28
What is Serevent (salmeterol) available as?
Diskus
29
What is the box warning for LABAs?
increased risk for asthma-related death (monotherapy) **only for use in combination with an ICS**
30
What are the side effects of beta-2 agonists?
Nervousness Tremor Tachycardia Palpitations Cough Hyperglycemia Decreased K+
31
What should be monitored for a patient taking an beta-2 agonists?
BP, HR blood glucose & K levels SABA only → frequency of use
32
List the brand/generic of LAMAs
Spiriva (tiotropium)
33
What is Spiriva (tiotropium) available as?
Respimat (1.25 mcg)
34
What is important to note about the use of LAMAs for asthma treatment?
Reserved as step 5 treatment for asthma -- add-on therapy (more common in COPD treatment)
35
Describe the "review" portion of personalized asthma management
review: symptoms, exacerbations, side-effects, lung function, comorbidities, satisfactions
36
Describe the "assess" portion of personalized asthma management
assess... Confirmation of diagnosis if necessary Symptom control & modifiable risk factors Comorbidities Inhaler technique & adherence Patient preferences & goals
37
Describe the "adjust" portion of personalized asthma management
adjust... Treatment of modifiable risk factors & comorbidities Non-pharmacological strategies Asthma medications including ICS (as below) Education & skills training
38
What is the reliever used in track 1: preferred controller & reliever?
as-needed low-dose ICS-formoterol
39
Why is ICS-formoterol the preferred reliever?
Using ICS-formoterol as the reliever reduces the risk of exacerbations compared with using a SABA reliever, and is a simpler regimen
40
What are the options for ICS/formoterol?
Symbicort (budesonide/formoterol) Dulera (mometasone/formoterol)
41
For a step 1-2 patient on track 1: preferred controller & reliever, what is the controller used?
As-needed-only low dose ICS-formoterol (only reliever)
42
For a step 3 patient on track 1: preferred controller & reliever, what is the controller used?
Low-dose maintenance ICS-formoterol
43
For a step 4 patient on track 1: preferred controller & reliever, what is the controller used?
Medium dose maintenance ICS-formoterol
44
What are the next steps for a step 5 patient on track 1: preferred controller & reliever?
Add-on LAMA Refer for assessment of phenotype Consider high dose maintenance ICS-formoterol +/- anti-IgE, anti-IL5/5R, anti-IL4R𝝰, anti-TSLP See GINA severe asthma guide
45
What is the reliever used in track 2: alternative controller & reliever?
as-needed ICS-SABA, or as-needed SABA
46
What is important to consider before considering a regimen with a SABA reliever?
whether or not the patient is likely to adhere to daily controller treatment
47
For a step 1 patient on track 2: alternative controller & reliever, what is the controller used?
Take ICS whenever SABA taken
48
For a step 2 patient on track 2: alternative controller & reliever, what is the controller used?
Low dose maintenance ICS
49
For a step 3 patient on track 2: alternative controller & reliever, what is the controller used?
Low dose maintenance ICS-LABA
50
For a step 4 patient on track 2: alternative controller & reliever, what is the controller used?
Medium/high dose maintenance ICS-LABA
51
What are the next steps for a step 5 patient on track 2: alternative controller & reliever?
Add-on LAMA Refer for assessment of phenotype Consider high dose maintenance ICS-formoterol +/- anti-IgE, anti-IL5/5R, anti-IL4R𝝰, anti-TSLP See GINA severe asthma guide
52
What is the follow-up timeframe for a patient what just initiated treatment or had a change in their regimen?
1-3 months after initiating treatment or change
53
What is the follow-up timeframe for a patient established on an asthma treatment regimen?
3-12 months
54
What should be considered before considering escalating therapy?
Prior to escalating therapy due to seemingly uncontrolled asthma, consider assessment of: Inhaler technique Adherence Trigger exposure
55
Describe the process of approaching de-escalating therapy
Can be considered after 2-3 months of maintained asthma control Patient-specific approach General principle → reduce ICS dose by 25-50% at 3-month intervals

PHRM 825 - Exam 3 (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions