Flashcards in Leptospirosis Deck (8)
Typical electrolyte abnormalities in leptospirosis
Hypokalemia and Hyponatremia
Electrolyte abnormality uniquely associated with leptospiral nephropathy
(Loss of magnesium in the urine)
Triad of Weil’s syndrome
Acute kidney injury
Definite diagnosis of leptospirosis
1. Isolation of organism from the patient
2. Positive result in PCR
3. Seroconversion or a rise in antibody titer (fourfold or greater rise in titer detected between acute and convalescent phase serum specimens)
Cross reactions occur with MAT (microagglutination test) with which diseases
What specimens can be used for culture during the first week?
CSF and Dialysate
What specimen can be used from the second week of symptomatic illness?
Urine (urinary excretion may last for several weeks)