LESSON 14 - exercise thresholds Flashcards

1
Q

what dose increasing lactate mean for protons ?

A

increasing protons

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2
Q

does increased lactate have an acidifying or basic effect

A

acidifying (increased protons (H+) = decreased pH)

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3
Q

what is buffering protons ?

A

neutralizing (keep us at that level)

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4
Q

what does bicarbonate do ?

A

compensate for that acidity

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5
Q

when bicarbonate combines with H what does it form ?

A

water and carbon dioxide

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6
Q

H + HCO3 produces H2O + CO2 uses what anhydrase ?

A

carbonic anhydrase

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7
Q

what keeps CO2 from accumulating and drives the carbonic anhydrase reactions towards production of CO2 and “consumption” of H+ ?

A

ventilation

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8
Q

what are the two metabolic boundaries ?

A
  • lactate threshold (LT)
  • critical intensity (CI) or maximal metabolic steady-state
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9
Q

describe lactate threshold :

A

the metabolic rate (or VO2) at which blood lactate cannot be maintained at resting levels

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10
Q

what types of intensity is lactate threshold ?

A

separates moderate from heavy intensity exercise domains

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11
Q

describe critical intensity or maximal metabolic steady-state :

A
  • the highest VO2 at which a heightened lactate production in muscle may be stabilized in blood
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12
Q

what types of intensity is critical intensity ?

A

separates heavy from severe intensity exercise domains

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13
Q

how can we detect these boundary crossings through incremental exercise ?

A

by measuring gas exchange and ventilation at the mouth

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14
Q

dissociating bicarbonate makes what ?

A

CO2 & H2O

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15
Q

for every O2 we produce about the same rate amount of what …

A

CO2

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16
Q

if we have no change in lactate (pH remains stable) what does this mean for bicarbonate ?

A

no bicarbonate since no buffering is needed

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17
Q

is lactate and pyruvate a reversible equation ?

18
Q

what is used to convert pyruvate to Lactate ?

A

lactate dehydrogenase

19
Q

at a low production, describe lactate appearance …

A

rate of lactate appearance equals disappearance

20
Q

below the lactate threshold (moderate) is hyperpnea or hyperventilation ?

A

hyperpnea (healthy amount)

21
Q

do we want a lot of lactate ?

A
  • no we do not
  • we want a low concentration in cytosol to maintain equilibrium
22
Q

where is lactate produced ?

A

in the muscle

23
Q

what is lactate associated with ?

A

with an increase in H+ ions

24
Q

above all else what is most important to maintain ?

A

H+ (bicarbonate plays a role in this)

25
we don't want too much pyruvate, but why do we need pyruvate ?
to support ATP rate demand
26
what does stopping pyruvate inhibit ?
glycolysis (dont want that)
27
when is steady state achieved ?
when lactate is stable
28
what organ replenishes bicarbonate ?
kidneys
29
moderate and heavy states are both examples of hyperpnea or hyperventilation ?
hyperpnea
30
what does it mean when lactate is elevates and unstable ?
- high production - rate of lactate appearance exceeds clearance
31
severe states is hyperpnea or hyperventilation ?
hyperventilation
32
what are the two metabolic thresholds ?
GET/VT1 and RCP/VT2
33
describe GET/VT1:
- the VO2 at the onset of bicarbonate buffering where VCO2 and VE begin to increase at a greater rate than VO2 - ≈ LT
34
what does GET/VT1 seperate ?
moderate from heavy intensity exercise domains
35
describe RCP/VT2 :
- the VO2 at which bicarbonate buffering cannot prevent acidosis and hyperventilation ensues to compensate - ≈ CI
36
what does RCP/VT2 separate ?
heavy from severe intensity exercise domains
37
is GET/VT1 hyperpnea or hyperventilation ?
hyperpnea
38
is RCP/VT2 hyperpnea or hyperventilation ?
hyperventilation
39
what does GET stand for ?
gas exchange threshold
40
what does RCP stand for ?
respiratory compensation point
41
describe the RCP performance two mile case performance :
- those with higher RCP had a better two mile rate - can be used to prove that better RCP = better performance