Flashcards in LFT Deck (28):
What is measured in a Liver function test?
Gamma Glutamyl transferase
What other factors are important to measure to see the health of the liver?
What are symptoms of liver disease?
Right upper quadrant pain
Colour of urine and stools
What are "red flags" for live disease in past medical history?
What are signs of liver disease on examination?
When is jaundice clinically apparent?
Bilirubin over 35
What is Gilbert's syndrome?
Isolated Mild Hyperbilirubinaemia
What is the cause of increased bilirubin production?
What are the causes of reduced hepatic uptake?
What are the reasons for a raised ALP ( alkaline phosphatase)
Bile duct obstruction
Primary sclerosing cholangitis
Primary Biliary cirrhosis
With respect to liver function tests what is found in bone marrow as well as liver?
ALP (Alkaline phosphatase)
What does a LFT measure?
Bilirubin, albumin and prothrombin time - true LFT
Test liver function test
What a liver damage tests?
Alanine amino transferase
Gamma Glutamyl transferase (GGT)
What are cholestatic Liver function tests?
These are enzymes that are damaged during biliary obstruction.
What are hepatitis/Hepatocellular LFT?
Alanine amino transferase (ALT)
What are true liver function tests?
What are the liver screening tests?
Alpha 1 antitrypsin
Caeuroluplasmin (low in wilsons)
What are the signs of cholestatic jaundice?
Post - hepatic jaundice
Pale stools, dark urine
What are the signs of gall stones?
What are the painless causes of jaundice?
Primary biliary cirrhosis - however would have a history
What is the single investigation you would do for jaundice?
This will be able to tell if the bile duct is dilated/not dilated.
After using an ultra sound and you find a dilated bile duct what should you do?
CT scan first
then ERCP - endoscopic retrograde cholangiopancreatography (allows you to remove the gall stone and bypass the lesion)
What would you do after an ultra sound if you find a non-dilated bile duct?
What does a non - dilated bile duct suggest?
What does dilated bile duct suggest?
What investigation would you do for suspected hepatitis?
How would you diagnose autoimmune hepatitis?